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Immuneering
IMRX

86 hedge funds and large institutions have $209M invested in Immuneering in 2025 Q4 according to their latest regulatory filings, with 31 funds opening new positions, 27 increasing their positions, 12 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

183% more call options, than puts

Call options by funds: $2.34M | Put options by funds: $828K

138% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 13

125% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 12

50% more funds holding in top 10

Funds holding in top 10: 2 → 3 (+1)

26% more funds holding

Funds holding: 68 → 86 (+18)

15% more capital invested

Capital invested by funds: $182M → $209M (+$26.6M)

13.48% less ownership

Funds ownership: 62.65% → 49.17% (-13%)

Holders
86
Holders Change
+18
Holders Change %
+26.47%
% of All Funds
1.05%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
31
Increased
27
Reduced
12
Closed
13
Calls
$2.34M
Puts
$828K
Net Calls
+$1.52M
Net Calls Change
+$1.52M

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$14.3M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$5.77M
3
BlackRock
BlackRock
New York
+$4.95M
4
Marshall Wace
Marshall Wace
United Kingdom
+$2.83M
5
Goldman Sachs
Goldman Sachs
New York
+$2.05M

Top Sellers

Rank Fund Capital Flow
1
ECM
ExodusPoint Capital Management
New York
-$10.6M
2
LGM
Logos Global Management
California
-$6.65M
3
Citadel Advisors
Citadel Advisors
Florida
-$5.47M
4
MIM
Monashee Investment Management
Massachusetts
-$2.1M
5
IAM
Iridian Asset Management
Connecticut
-$1.93M
Name Holding Trade Value Shares
Change 		Change in
Stake
Connor, Clark & Lunn Investment Management (CC&L)
26
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$873K +$852K +132,680 New
Rafferty Asset Management
27
Rafferty Asset Management
New York
$860K +$839K +130,742 New
BCM
28
Bridgeway Capital Management
Texas
$793K – – –
KWM
29
Kingsview Wealth Management
Oregon
$780K +$184K +28,600 +32%
TD Asset Management
30
TD Asset Management
Ontario, Canada
$775K -$175K -27,334 -19%
HighTower Advisors
31
HighTower Advisors
Illinois
$733K -$136K -21,135 -16%
Northern Trust
32
Northern Trust
Illinois
$718K +$109K +17,021 +18%
Susquehanna International Group
33
Susquehanna International Group
Pennsylvania
$707K +$690K +107,472 New
Jane Street
34
Jane Street
New York
$671K +$655K +102,034 New
Squarepoint
35
Squarepoint
New York
$607K +$592K +92,256 New
Citadel Advisors
36
Citadel Advisors
Florida
$595K -$5.47M -852,685 -90%
Hudson Bay Capital Management
37
Hudson Bay Capital Management
Connecticut
$559K -$112K -17,475 -17%
LCM
38
Landscape Capital Management
New Jersey
$542K +$529K +82,349 New
PCM
39
Prelude Capital Management
New York
$526K +$48.4K +7,533 +10%
Manulife (Manufacturers Life Insurance)
40
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$469K +$2.98K +464 +0.7%
PWM
41
Palumbo Wealth Management
New York
$416K +$91.3K +14,221 +29%
FRM
42
Fox Run Management
Connecticut
$341K +$332K +51,773 New
Millennium Management
43
Millennium Management
New York
$335K -$1.19M -185,858 -78%
OAC
44
OMERS Administration Corp
Ontario, Canada
$315K +$307K +47,800 New
PA
45
Profund Advisors
Maryland
$310K +$303K +47,135 New
FCC
46
Flower City Capital
New York
$278K +$83.5K +13,000 +44%
Citigroup
47
Citigroup
New York
$247K +$236K +36,741 +4,616%
Corient Private Wealth
48
Corient Private Wealth
Florida
$236K -$1.41K -220 -0.6%
Two Sigma Advisers
49
Two Sigma Advisers
New York
$209K +$204K +31,800 New
EC
50
EntryPoint Capital
New York
$206K +$201K +31,237 New
1
2
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IMRX Hedge Fund Activity: Q4 2025 in Review

86 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in Immuneering (IMRX) for Q4 2025, worth a combined $209M — up 15% from $182M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new IMRX positions and 13 closed out — a net gain of 18 holders — while 27 added to existing stakes and 12 trimmed.

The largest buyer was State Street, adding an estimated $14.3M. The largest seller was ExodusPoint Capital Management, exiting entirely with an estimated $10.6M sold.

  • 86 institutional investors held Immuneering (IMRX) as of Q4 2025, up from 68 in Q3 2025.
  • Funds reported $209M of Immuneering stock for Q4 2025, up 15% quarter-over-quarter.
  • 31 funds opened new Immuneering positions in Q4 2025 and 13 closed out, a net change of +18 holders.
  • The largest Immuneering buyer in Q4 2025 was State Street, an estimated $14.3M added.
  • The largest Immuneering seller in Q4 2025 was ExodusPoint Capital Management, an estimated $10.6M sold.

Based on aggregated 13F filings for Q4 2025.