|
1
|
RA Capital Management
Boston,
Massachusetts
|
$150M
|
+$11.3M
|
+1,824,000
|
+10%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$112M
|
+$3.23M
|
+520,129
|
+4%
|
|
|
3
|
|
$110M
|
-$3.22M
|
-518,571
|
-3%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$103M
|
-$1.03M
|
-165,610
|
-1%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$91.1M
|
+$4.41M
|
+709,936
|
+6%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$76.3M
|
+$15.8M
|
+2,536,193
|
+33%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$61.3M
|
–
|
–
|
–
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$59.9M
|
-$6.2M
|
-997,290
|
-11%
|
|
|
9
|
ClearBridge Investments
New York
|
$43.7M
|
-$547K
|
-88,079
|
-1%
|
|
|
10
|
Millennium Management
New York
|
$37.5M
|
+$13.1M
|
+2,101,770
|
+71%
|
|
|
11
|
|
$31.2M
|
+$2.75M
|
+443,017
|
+12%
|
|
|
12
|
|
$28.7M
|
-$68.5M
|
-11,029,128
|
-74%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$28.7M
|
+$24M
|
+3,861,498
|
New
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$26.3M
|
+$823K
|
+132,422
|
+4%
|
|
|
15
|
Lombard Odier Asset Management (Switzerland)
Petit-Lancy,
Switzerland
|
$25.6M
|
+$2.67M
|
+430,057
|
+14%
|
|
|
16
|
Two Sigma Investments
New York
|
$19M
|
+$3.07M
|
+494,108
|
+24%
|
|
|
17
|
Two Sigma Advisers
New York
|
$16M
|
+$78.3K
|
+12,596
|
+0.6%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$15.8M
|
+$131K
|
+21,104
|
+1%
|
|
|
19
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
$15.8M
|
+$13.2M
|
+2,129,531
|
New
|
|
|
20
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$15.4M
|
+$4.18M
|
+672,900
|
+48%
|
|
|
21
|
|
$14.4M
|
+$12M
|
+1,934,900
|
New
|
|
|
22
|
|
$13.8M
|
-$1.42M
|
-228,529
|
-11%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$13.7M
|
+$38.5K
|
+6,194
|
+0.3%
|
|
|
24
|
Sofinnova Investments
Menlo Park,
California
|
$13M
|
+$10.9M
|
+1,749,882
|
New
|
|
|
25
|
Silverarc Capital Management
Boston,
Massachusetts
|
$11.2M
|
+$5.37M
|
+864,492
|
+133%
|
|
