|
1
|
Baker Bros. Advisors
New York
|
$107M
|
+$112M
|
+2,520,730
|
New
|
|
|
2
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$97.6M
|
+$102M
|
+2,292,285
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$60.5M
|
+$63.3M
|
+1,421,137
|
New
|
|
|
4
|
|
$50.1M
|
+$55.5M
|
+1,245,532
|
New
|
|
|
5
|
|
$46M
|
+$48.1M
|
+1,080,125
|
New
|
|
|
6
|
General Atlantic
New York
|
$40.4M
|
+$42.3M
|
+950,000
|
New
|
|
|
7
|
Gates Foundation
Seattle,
Washington
|
$24.6M
|
+$25.7M
|
+576,923
|
New
|
|
|
8
|
Avidity Partners Management
Dallas,
Texas
|
$23.4M
|
+$24.5M
|
+550,000
|
New
|
|
|
9
|
Perceptive Advisors
New York
|
$17M
|
+$17.8M
|
+400,000
|
New
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$16.5M
|
+$17.3M
|
+387,912
|
New
|
|
|
11
|
Thrivent Financial for Lutherans
Minneapolis,
Minnesota
|
$13.6M
|
+$14.3M
|
+320,252
|
New
|
|
|
12
|
Bain Capital Public Equity Management II
Boston,
Massachusetts
|
$12.8M
|
+$13.4M
|
+300,871
|
New
|
|
|
13
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$11.9M
|
+$12.4M
|
+279,580
|
New
|
|
|
14
|
Wellington Management Group
Boston,
Massachusetts
|
$10.5M
|
+$11M
|
+247,358
|
New
|
|
|
15
|
Millennium Management
New York
|
$8.67M
|
+$9.07M
|
+203,655
|
New
|
|
|
16
|
|
$8.51M
|
+$8.9M
|
+200,000
|
New
|
|
|
17
|
Deerfield Management
New York
|
$7.32M
|
+$7.65M
|
+171,908
|
New
|
|
|
18
|
|
$6.41M
|
+$6.71M
|
+150,658
|
New
|
|
|
19
|
Tybourne Capital Management
Hong Kong
|
$5.88M
|
+$6.15M
|
+138,192
|
New
|
|
|
20
|
Principal Financial Group
Des Moines,
Iowa
|
$5.26M
|
+$5.5M
|
+123,572
|
New
|
|
|
21
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$4.15M
|
+$4.34M
|
+97,502
|
New
|
|
|
22
|
Samsara BioCapital
Palo Alto,
California
|
$3.41M
|
+$3.56M
|
+80,000
|
New
|
|
|
23
|
Marshall Wace North America
New York
|
$2.63M
|
+$2.75M
|
+61,758
|
New
|
|
|
24
|
Omega Fund Management
Boston,
Massachusetts
|
$2.19M
|
+$2.29M
|
+51,535
|
New
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$2.19M
|
+$2.29M
|
+51,436
|
New
|
|
