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Illumina

859 hedge funds and large institutions have $20.8B invested in Illumina in 2025 Q4 according to their latest regulatory filings, with 176 funds opening new positions, 302 increasing their positions, 271 reducing their positions, and 80 closing their positions.

New
Increased
Maintained
Reduced
Closed

195% more call options, than puts

Call options by funds: $406M | Put options by funds: $138M

120% more first-time investments, than exits

New positions opened: 176 | Existing positions closed: 80

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

39% more capital invested

Capital invested by funds: $14.9B → $20.8B (+$5.85B)

11% more repeat investments, than reductions

Existing positions increased: 302 | Existing positions reduced: 271

11% more funds holding

Funds holding: 777859 (+82)

1.26% more ownership

Funds ownership: 102.26%103.52% (+1.3%)

Holders
859
Holders Change
+82
Holders Change %
+10.55%
% of All Funds
10.39%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.16%
New
176
Increased
302
Reduced
271
Closed
80
Calls
$406M
Puts
$138M
Net Calls
+$269M
Net Calls Change
-$226M

ILMN Hedge Fund Activity: Q4 2025 in Review

859 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Illumina (ILMN) for Q4 2025, worth a combined $20.8B — up 39% from $14.9B a quarter earlier.

Buyers outnumbered sellers: 176 funds opened new ILMN positions and 80 closed out — a net gain of 96 holders — while 302 added to existing stakes and 271 trimmed.

The largest buyer was Invesco, adding an estimated $159M. The largest seller was Sessa Capital, cutting an estimated $151M.

  • 859 institutional investors held Illumina (ILMN) as of Q4 2025, up from 777 in Q3 2025.
  • Funds reported $20.8B of Illumina stock for Q4 2025, up 39% quarter-over-quarter.
  • 176 funds opened new Illumina positions in Q4 2025 and 80 closed out, a net change of +96 holders.
  • The largest Illumina buyer in Q4 2025 was Invesco, an estimated $159M added.
  • The largest Illumina seller in Q4 2025 was Sessa Capital, an estimated $151M sold.

Based on aggregated 13F filings for Q4 2025.