|
1
|
Baker Bros. Advisors
New York
|
$25M
|
+$23.7K
|
+1,994
|
+0%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$21.8M
|
-$5.29M
|
-445,260
|
-11%
|
|
|
3
|
Siren LLC
Greenwich,
Connecticut
|
$20.3M
|
–
|
–
|
–
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$18M
|
-$1.43M
|
-120,347
|
-4%
|
|
|
5
|
|
$8.79M
|
+$17.1M
|
+1,438,975
|
New
|
|
|
6
|
|
$6.44M
|
+$1.83M
|
+154,107
|
+17%
|
|
|
7
|
|
$5.98M
|
-$3.34M
|
-280,745
|
-22%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.48M
|
+$73.1K
|
+6,150
|
+0.7%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$2.89M
|
-$4.11M
|
-346,103
|
-42%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$2.81M
|
-$123K
|
-10,339
|
-2%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$2.5M
|
+$158K
|
+13,334
|
+3%
|
|
|
12
|
Northern Trust
Chicago,
Illinois
|
$1.18M
|
+$15.6K
|
+1,312
|
+0.7%
|
|
|
13
|
TD Asset Management
Toronto,
Ontario, Canada
|
$1M
|
–
|
–
|
–
|
|
|
14
|
Charles Schwab
San Francisco,
California
|
$964K
|
+$112K
|
+9,441
|
+6%
|
|
|
15
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$770K
|
-$706K
|
-59,395
|
-32%
|
|
|
16
|
Two Sigma Investments
New York
|
$658K
|
+$848K
|
+71,343
|
+197%
|
|
|
17
|
Wellington Management Group
Boston,
Massachusetts
|
$617K
|
+$32.3K
|
+2,716
|
+3%
|
|
|
18
|
Bruce & Co
Chicago,
Illinois
|
$611K
|
–
|
–
|
–
|
|
|
19
|
|
$592K
|
-$8.82K
|
-742
|
-0.8%
|
|
|
20
|
GSA Capital Partners
London,
United Kingdom
|
$571K
|
+$436K
|
+36,728
|
+65%
|
|
|
21
|
Millennium Management
New York
|
$510K
|
-$581K
|
-48,874
|
-37%
|
|
|
22
|
Renaissance Technologies
New York
|
$463K
|
+$110K
|
+9,300
|
+14%
|
|
|
23
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$441K
|
-$29.2K
|
-2,457
|
-3%
|
|
|
24
|
Woodline Partners
San Francisco,
California
|
$411K
|
–
|
–
|
–
|
|
|
25
|
Bank of New York Mellon
New York
|
$290K
|
+$13.7K
|
+1,154
|
+2%
|
|
