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IBIO

Name Holding Trade Value Shares
Change 		Change in
Stake
EC
1
EcoR1 Capital
California
$4.3M +$3.04M +2,228,000 New
AAA
2
Affinity Asset Advisors
New York
$3.97M +$2.81M +2,057,200 New
LGM
3
Logos Global Management
California
$3.86M +$2.73M +2,000,000 New
FLSM
4
Frazier Life Sciences Management
California
$3.77M +$2.67M +1,953,467 New
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$2.12M +$1.48M +1,085,779 +10,440%
IC
6
Ikarian Capital
Texas
$1.85M +$464K +339,735 +55%
Vanguard Group
7
Vanguard Group
Pennsylvania
$1.7M +$831K +609,079 +222%
SCM
8
Sio Capital Management
New York
$1.43M +$1.01M +740,000 New
Ameriprise
9
Ameriprise
Minnesota
$1.13M +$139K +102,068 +21%
Two Sigma Investments
10
Two Sigma Investments
New York
$881K +$623K +456,333 New
ACM
11
ADAR1 Capital Management
Texas
$783K +$517K +378,531 +1,402%
Renaissance Technologies
12
Renaissance Technologies
New York
$682K +$482K +353,339 New
MIM
13
Monashee Investment Management
Massachusetts
$530K +$375K +274,862 New
BFM
14
Boothbay Fund Management
New York
$491K +$106K +77,550 +44%
Hudson Bay Capital Management
15
Hudson Bay Capital Management
Connecticut
$467K +$330K +242,076 New
NCM
16
Noesis Capital Mangement
Florida
$433K +$306K +224,200 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$430K +$97.3K +71,301 +47%
Walleye Capital
18
Walleye Capital
New York
$383K +$271K +198,375 New
JFG
19
Jefferies Financial Group
New York
$309K +$218K +160,000 New
UBS Group
20
UBS Group
Switzerland
$244K +$173K +126,555 +12,655,500%
Marshall Wace
21
Marshall Wace
United Kingdom
$234K +$166K +121,286 New
Bank of America
22
Bank of America
North Carolina
$223K +$158K +115,648 +79,757%
Two Sigma Advisers
23
Two Sigma Advisers
New York
$209K +$148K +108,400 New
SCM
24
Silverarc Capital Management
Massachusetts
$205K +$145K +106,000 New
Jane Street
25
Jane Street
New York
$204K +$144K +105,700 New
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