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iBio
IBIO

50 hedge funds and large institutions have $31.6M invested in iBio in 2025 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 12 increasing their positions, 3 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

968% more capital invested

Capital invested by funds: $2.96M → $31.6M (+$28.6M)

300% more repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 3

225% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 8

56% more funds holding

Funds holding: 32 → 50 (+18)

54.5% more ownership

Funds ownership: 18.16% → 72.66% (+54%)

Holders
50
Holders Change
+18
Holders Change %
+56.25%
% of All Funds
0.61%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
26
Increased
12
Reduced
3
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$3.04M
2
AAA
Affinity Asset Advisors
New York
+$2.81M
3
LGM
Logos Global Management
California
+$2.73M
4
FLSM
Frazier Life Sciences Management
California
+$2.67M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$1.48M

Top Sellers

Rank Fund Capital Flow
1
LCM
Lynx1 Capital Management
Puerto Rico
-$874K
2
OM
Opaleye Management
Massachusetts
-$310K
3
Citadel Advisors
Citadel Advisors
Florida
-$109K
4
TSS
Two Sigma Securities
New York
-$37.3K
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$36.8K
Name Holding Trade Value Shares
Change 		Change in
Stake
EC
1
EcoR1 Capital
California
$4.3M +$3.04M +2,228,000 New
AAA
2
Affinity Asset Advisors
New York
$3.97M +$2.81M +2,057,200 New
LGM
3
Logos Global Management
California
$3.86M +$2.73M +2,000,000 New
FLSM
4
Frazier Life Sciences Management
California
$3.77M +$2.67M +1,953,467 New
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$2.12M +$1.48M +1,085,779 +10,440%
IC
6
Ikarian Capital
Texas
$1.85M +$464K +339,735 +55%
Vanguard Group
7
Vanguard Group
Pennsylvania
$1.7M +$831K +609,079 +222%
SCM
8
Sio Capital Management
New York
$1.43M +$1.01M +740,000 New
Ameriprise
9
Ameriprise
Minnesota
$1.13M +$139K +102,068 +21%
Two Sigma Investments
10
Two Sigma Investments
New York
$881K +$623K +456,333 New
ACM
11
ADAR1 Capital Management
Texas
$783K +$517K +378,531 +1,402%
Renaissance Technologies
12
Renaissance Technologies
New York
$682K +$482K +353,339 New
MIM
13
Monashee Investment Management
Massachusetts
$530K +$375K +274,862 New
BFM
14
Boothbay Fund Management
New York
$491K +$106K +77,550 +44%
Hudson Bay Capital Management
15
Hudson Bay Capital Management
Connecticut
$467K +$330K +242,076 New
NCM
16
Noesis Capital Mangement
Florida
$433K +$306K +224,200 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$430K +$97.3K +71,301 +47%
Walleye Capital
18
Walleye Capital
New York
$383K +$271K +198,375 New
JFG
19
Jefferies Financial Group
New York
$309K +$218K +160,000 New
UBS Group
20
UBS Group
Switzerland
$244K +$173K +126,555 +12,655,500%
Marshall Wace
21
Marshall Wace
United Kingdom
$234K +$166K +121,286 New
Bank of America
22
Bank of America
North Carolina
$223K +$158K +115,648 +79,757%
Two Sigma Advisers
23
Two Sigma Advisers
New York
$209K +$148K +108,400 New
SCM
24
Silverarc Capital Management
Massachusetts
$205K +$145K +106,000 New
Jane Street
25
Jane Street
New York
$204K +$144K +105,700 New
1
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IBIO Hedge Fund Activity: Q4 2025 in Review

50 of the 8,232 institutional investors tracked by Wall St. Rank reported a position in iBio (IBIO) for Q4 2025, worth a combined $31.6M — up 968% from $2.96M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IBIO positions and 8 closed out — a net gain of 18 holders — while 12 added to existing stakes and 3 trimmed.

The largest buyer was EcoR1 Capital, opening a new position worth an estimated $3.04M. The largest seller was Lynx1 Capital Management, exiting entirely with an estimated $874K sold.

  • 50 institutional investors held iBio (IBIO) as of Q4 2025, up from 32 in Q3 2025.
  • Funds reported $31.6M of iBio stock for Q4 2025, up 968% quarter-over-quarter.
  • 26 funds opened new iBio positions in Q4 2025 and 8 closed out, a net change of +18 holders.
  • The largest iBio buyer in Q4 2025 was EcoR1 Capital, an estimated $3.04M added.
  • The largest iBio seller in Q4 2025 was Lynx1 Capital Management, an estimated $874K sold.

Based on aggregated 13F filings for Q4 2025.