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iShares Biotechnology ETF
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Overview Fund Activity

782 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 342 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
782
Holders Change
-39
Holders Change %
-4.75%
% of All Funds
10.49%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
342
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
C
776
Covestor
United Kingdom
$1K +$1K +4 New
FCMT
777
Founders Capital Management (Texas)
Texas
$771 – – –
CPBTD
778
Central Pacific Bank - Trust Division
Hawaii
$633 – – –
LC
779
Luminist Capital
Michigan
$511 – – –
WPWM
780
Western Pacific Wealth Management
Illinois
$382 – – –
NRG
781
Nemes Rush Group
Michigan
$253 -$807K -6,379 -100%
MCM
782
Manchester Capital Management
Vermont
$127 – – –
SSG
783
Summit Securities Group
New York
$127 +$127 +1 New
OLVIG
784
Oliver Lagore Vanvalin Investment Group
Michigan
$59 – – –
MMEA
785
Main Management ETF Advisors
California
– -$78.3M -612,180 Closed
Two Sigma Investments
786
Two Sigma Investments
New York
– -$35.5M -277,807 Closed
MFS
787
Madrona Financial Services
Washington
– -$10.4M -81,150 Closed
GS
788
GTS Securities
New York
– -$9.26M -72,376 Closed
MIG
789
McGuire Investment Group
Rhode Island
– -$7.64M -59,752 Closed
D.E. Shaw & Co
790
D.E. Shaw & Co
New York
– -$7.01M -54,801 Closed
SA
791
Sicart Associates
New York
– -$5.82M -45,503 Closed
MCP
792
Mirador Capital Partners
California
– -$3.92M -30,626 Closed
PFA
793
Pinnacle Family Advisors
Missouri
– -$3.04M -23,806 Closed
HI
794
Hudock Inc
Pennsylvania
– -$2.63M -20,538 Closed
Twin Tree Management
795
Twin Tree Management
Texas
– -$2.56M -20,002 Closed
GS
796
GWN Securities
Florida
– -$2.14M -18,146 Closed
AFA
797
Arlington Financial Advisors
California
– -$2.16M -16,861 Closed
HAC
798
Harbor Advisory Corp
New Hampshire
– -$1.5M -11,761 Closed
PWP
799
Pursue Wealth Partners
California
– -$1.42M -11,137 Closed
SC
800
SummitTX Capital
Texas
– -$1.4M -10,970 Closed
30 31
32
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