|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$139M
|
-$69.3M
|
-2,308,914
|
-32%
|
|
|
2
|
Vivo Capital
Palo Alto,
California
|
$128M
|
–
|
–
|
–
|
|
|
3
|
venBio Partners
San Francisco,
California
|
$98.9M
|
–
|
–
|
–
|
|
|
4
|
Newlight Partners
New York
|
$75.3M
|
-$73.2K
|
-2,441
|
-0.1%
|
|
|
5
|
Novo Holdings A/S
Hellerup,
Denmark
|
$40.2M
|
-$57.4M
|
-1,913,425
|
-57%
|
|
|
6
|
|
$36.8M
|
+$30.2M
|
+1,006,289
|
+337%
|
|
|
7
|
Janus Henderson Group
London,
|
$35.6M
|
+$3.23M
|
+107,609
|
+9%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$32.8M
|
+$10.5M
|
+350,935
|
+43%
|
|
|
9
|
Aisling Capital Management
New York
|
$23.8M
|
–
|
–
|
–
|
|
|
10
|
Nan Fung Group Holdings
Kai Tak,
Hong Kong
|
$21.7M
|
+$23.1M
|
+768,708
|
New
|
|
|
11
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$19.1M
|
+$2.15M
|
+71,755
|
+12%
|
|
|
12
|
Ashford Capital Management
Wilmington,
Delaware
|
$18M
|
-$259K
|
-8,640
|
-1%
|
|
|
13
|
Perceptive Advisors
New York
|
$13.9M
|
+$5.39M
|
+179,659
|
+58%
|
|
|
14
|
Nuveen
Charlotte,
North Carolina
|
$9.39M
|
+$8.31M
|
+276,981
|
+497%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$8.55M
|
+$6.46M
|
+215,312
|
+246%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$6.35M
|
+$3.73M
|
+124,185
|
+123%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$5.37M
|
+$3.64M
|
+121,335
|
+176%
|
|
|
18
|
American Century Companies
Kansas City,
Missouri
|
$5.33M
|
+$1.13M
|
+37,650
|
+25%
|
|
|
19
|
International Biotechnology Trust
London,
United Kingdom
|
$4.69M
|
+$4.98M
|
+166,000
|
New
|
|
|
20
|
Burrage Capital Management
Boston,
Massachusetts
|
$4.23M
|
–
|
–
|
–
|
|
|
21
|
Millennium Management
New York
|
$4.2M
|
+$4.24M
|
+141,270
|
+1,846%
|
|
|
22
|
Rice Hall James & Associates
San Diego,
California
|
$3.96M
|
-$194K
|
-6,467
|
-4%
|
|
|
23
|
|
$3.63M
|
+$1.95M
|
+64,929
|
+102%
|
|
|
24
|
Royce & Associates
New York
|
$3.62M
|
+$3.84M
|
+128,050
|
New
|
|
|
25
|
Ghost Tree Capital
New York
|
$3.53M
|
+$3.75M
|
+125,000
|
New
|
|
