|
1
|
Baker Bros. Advisors
New York
|
$4.81M
|
–
|
–
|
–
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$3.38M
|
+$890K
|
+112,230
|
+24%
|
|
|
3
|
|
$3.35M
|
–
|
–
|
–
|
|
|
4
|
Knoll Capital Management
Miami,
Florida
|
$3.26M
|
–
|
–
|
–
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$2.01M
|
+$36.2K
|
+4,562
|
+1%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$1.25M
|
+$1.63K
|
+205
|
+0.1%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$630K
|
–
|
–
|
–
|
|
|
8
|
Acadian Asset Management
Boston,
Massachusetts
|
$586K
|
+$86.3K
|
+10,885
|
+12%
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
$419K
|
+$34.3K
|
+4,322
|
+7%
|
|
|
10
|
Renaissance Technologies
New York
|
$179K
|
+$66.4K
|
+8,380
|
+38%
|
|
|
11
|
|
$140K
|
-$796K
|
-100,415
|
-81%
|
|
|
12
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$127K
|
+$4.08K
|
+514
|
+2%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$100K
|
+$7.53K
|
+950
|
+6%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$92.7K
|
-$159
|
-20
|
-0.1%
|
|
|
15
|
|
$73.8K
|
-$131K
|
-16,462
|
-57%
|
|
|
16
|
Two Sigma Investments
New York
|
$71.9K
|
+$21.2K
|
+2,671
|
+28%
|
|
|
17
|
GSA Capital Partners
London,
United Kingdom
|
$71K
|
+$94.9K
|
+11,964
|
New
|
|
|
18
|
Prudential Financial
Newark,
New Jersey
|
$38.2K
|
–
|
–
|
–
|
|
|
19
|
Group One Trading
Chicago,
Illinois
|
$34.9K
|
+$33K
|
+4,160
|
+239%
|
|
|
20
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$30K
|
-$102K
|
-12,866
|
-72%
|
|
|
21
|
Tyler-Stone Wealth Management
Beachwood,
Ohio
|
$28K
|
+$190
|
+24
|
+0.5%
|
|
|
22
|
Two Sigma Advisers
New York
|
$27.8K
|
+$8.96K
|
+1,130
|
+32%
|
|
|
23
|
Tower Research Capital (TRC)
New York
|
$25.2K
|
+$25.5K
|
+3,216
|
+308%
|
|
|
24
|
Millennium Management
New York
|
$23.8K
|
-$817
|
-103
|
-3%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$21.5K
|
+$95
|
+12
|
+0.3%
|
|
