Halozyme
HALO
603 hedge funds and large institutions have $8.75B invested in Halozyme in 2025 Q3 according to their latest regulatory filings, with 112 funds opening new positions, 186 increasing their positions, 239 reducing their positions, and 52 closing their positions.
115% more first-time investments, than exits
New positions opened: 112 | Existing positions closed: 52
67% more funds holding in top 10
Funds holding in top 10: 3 → 5 (+2)
52% more call options, than puts
Call options by funds: $52.5M | Put options by funds: $34.7M
45% more capital invested
Capital invested by funds: $6.05B → $8.75B (+$2.69B)
9% more funds holding
Funds holding: 551 → 603 (+52)
7.59% more ownership
Funds ownership: 94.38% → 101.97% (+7.6%)
22% less repeat investments, than reductions
Existing positions increased: 186 | Existing positions reduced: 239
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
D.E. Shaw & Co
New York
|
+$108M |
| 2 |
UBS Group
Zurich,
Switzerland
|
+$94.4M |
| 3 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
+$71.9M |
| 4 |
Voloridge Investment Management
Jupiter,
Florida
|
+$70.3M |
| 5 |
Two Sigma Investments
New York
|
+$58.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
State Street
Boston,
Massachusetts
|
-$60.8M |
| 2 |
Artisan Partners
Milwaukee,
Wisconsin
|
-$50M |
| 3 |
Goldman Sachs
New York
|
-$45.4M |
| 4 |
SCM
Snyder Capital Management
San Francisco,
California
|
-$44.1M |
| 5 |
Vanguard Group
Malvern,
Pennsylvania
|
-$40.9M |
HALO Hedge Fund Activity: Q3 2025 in Review
603 of the 7,640 institutional investors tracked by Wall St. Rank reported a position in Halozyme (HALO) for Q3 2025, worth a combined $8.75B — up 45% from $6.05B a quarter earlier.
Buyers outnumbered sellers: 112 funds opened new HALO positions and 52 closed out — a net gain of 60 holders — while 186 added to existing stakes and 239 trimmed.
The largest buyer was D.E. Shaw & Co, adding an estimated $108M. The largest seller was State Street, cutting an estimated $60.8M.
- 603 institutional investors held Halozyme (HALO) as of Q3 2025, up from 551 in Q2 2025.
- Funds reported $8.75B of Halozyme stock for Q3 2025, up 45% quarter-over-quarter.
- 112 funds opened new Halozyme positions in Q3 2025 and 52 closed out, a net change of +60 holders.
- The largest Halozyme buyer in Q3 2025 was D.E. Shaw & Co, an estimated $108M added.
- The largest Halozyme seller in Q3 2025 was State Street, an estimated $60.8M sold.
Based on aggregated 13F filings for Q3 2025.