|
1
|
Sofinnova Investments
Menlo Park,
California
|
$4.01M
|
–
|
–
|
–
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$3.2M
|
–
|
–
|
–
|
|
|
3
|
|
$2.18M
|
–
|
–
|
–
|
|
|
4
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.17M
|
–
|
–
|
–
|
|
|
5
|
Nan Fung Group Holdings
Kai Tak,
Hong Kong
|
$797K
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$567K
|
-$2.41K
|
-1,409
|
-0.3%
|
|
|
7
|
|
$410K
|
-$11.4K
|
-6,633
|
-2%
|
|
|
8
|
Renaissance Technologies
New York
|
$315K
|
-$337K
|
-196,782
|
-45%
|
|
|
9
|
Bridgeway Capital Management
Houston,
Texas
|
$243K
|
+$68.5K
|
+40,000
|
+27%
|
|
|
10
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$197K
|
+$192K
|
+112,002
|
+282%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$103K
|
–
|
–
|
–
|
|
|
12
|
Two Sigma Investments
New York
|
$76K
|
-$174K
|
-101,373
|
-63%
|
|
|
13
|
Two Sigma Advisers
New York
|
$66K
|
-$170K
|
-99,200
|
-66%
|
|
|
14
|
Crestline Management
Fort Worth,
Texas
|
$45K
|
-$760
|
-444
|
-1%
|
|
|
15
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$39K
|
-$50.6K
|
-29,546
|
-49%
|
|
|
16
|
BIT Capital
Berlin,
Germany
|
$39K
|
-$34.3K
|
-20,000
|
-40%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$37K
|
–
|
–
|
–
|
|
|
18
|
Raymond James Financial Services Advisors
St. Petersburg,
Florida
|
$29K
|
–
|
–
|
–
|
|
|
19
|
Millennium Management
New York
|
$24K
|
-$65.2K
|
-38,051
|
-67%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$24K
|
–
|
–
|
–
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$21K
|
-$210K
|
-122,654
|
-89%
|
|
|
22
|
|
$19K
|
+$3.48K
|
+2,030
|
+16%
|
|
|
23
|
HSBC Holdings
London,
United Kingdom
|
$17K
|
-$260
|
-152
|
-1%
|
|
|
24
|
|
$15K
|
-$7.2K
|
-4,201
|
-27%
|
|
|
25
|
|
$15K
|
+$19.9K
|
+11,599
|
New
|
|
