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Monte Rosa Therapeutics

105 hedge funds and large institutions have $276M invested in Monte Rosa Therapeutics in 2025 Q1 according to their latest regulatory filings, with 22 funds opening new positions, 23 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more call options, than puts

Call options by funds: $413K | Put options by funds: $206K

5% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 21

1% more funds holding

Funds holding: 104105 (+1)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

2.49% less ownership

Funds ownership: 99.26%96.77% (-2.5%)

35% less capital invested

Capital invested by funds: $423M → $276M (-$147M)

48% less repeat investments, than reductions

Existing positions increased: 23 | Existing positions reduced: 44

Holders
105
Holders Change
+1
Holders Change %
+0.96%
% of All Funds
1.41%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
22
Increased
23
Reduced
44
Closed
21
Calls
$413K
Puts
$206K
Net Calls
+$207K
Net Calls Change
-$1.84M
Name Holding Trade Value Shares
Change
Change in
Stake
NMC
1
NEA Management Company
Maryland
$35.7M
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$30.8M -$2.9M -472,501 -7%
BI
3
BVF Inc
California
$26.3M +$17.8M +2,895,661 +105%
VVM
4
Versant Venture Management
California
$26.2M
BBA
5
Baker Bros. Advisors
New York
$22.8M
Fidelity Investments
6
Fidelity Investments
Massachusetts
$21.7M -$5.36M -874,340 -16%
ACA
7
Avoro Capital Advisors
New York
$21.6M +$1.84M +300,548 +7%
BlackRock
8
BlackRock
New York
$17.5M -$450K -73,452 -2%
Vanguard Group
9
Vanguard Group
Pennsylvania
$14.4M -$345K -56,318 -2%
SCM
10
Suvretta Capital Management
New York
$7.26M
ACM
11
Aisling Capital Management
New York
$6.83M
AI
12
Alphabet Inc
California
$6.79M
Geode Capital Management
13
Geode Capital Management
Massachusetts
$4.66M -$200K -32,603 -3%
State Street
14
State Street
Massachusetts
$3.72M -$1.69M -275,173 -26%
PL
15
Parkwood LLC
Ohio
$3.29M +$2.36M +385,000 +119%
Morgan Stanley
16
Morgan Stanley
New York
$1.96M -$11.2M -1,833,263 -81%
Northern Trust
17
Northern Trust
Illinois
$1.73M -$23K -3,757 -1%
Marshall Wace
18
Marshall Wace
United Kingdom
$1.72M -$783K -127,754 -26%
Charles Schwab
19
Charles Schwab
California
$1.68M -$54.8K -8,937 -2%
Goldman Sachs
20
Goldman Sachs
New York
$1.65M +$1.2M +196,238 +123%
Millennium Management
21
Millennium Management
New York
$1.53M +$1.74M +284,097 +613%
RAM
22
Readystate Asset Management
Illinois
$1.33M +$1.76M +287,000 New
Dimensional Fund Advisors
23
Dimensional Fund Advisors
Texas
$1.22M +$725K +118,179 +82%
AQR Capital Management
24
AQR Capital Management
Connecticut
$1.07M +$1.41M +229,536 New
Two Sigma Investments
25
Two Sigma Investments
New York
$1.04M -$341K -55,655 -20%

GLUE Hedge Fund Activity: Q1 2025 in Review

105 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Monte Rosa Therapeutics (GLUE) for Q1 2025, worth a combined $276M — down 35% from $423M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new GLUE positions and 21 closed out — a net gain of 1 holder — while 23 added to existing stakes and 44 trimmed.

The largest buyer was BVF Inc, adding an estimated $17.8M. The largest seller was Morgan Stanley, cutting an estimated $11.2M.

  • 105 institutional investors held Monte Rosa Therapeutics (GLUE) as of Q1 2025, up from 104 in Q4 2024.
  • Funds reported $276M of Monte Rosa Therapeutics stock for Q1 2025, down 35% quarter-over-quarter.
  • 22 funds opened new Monte Rosa Therapeutics positions in Q1 2025 and 21 closed out, a net change of +1 holder.
  • The largest Monte Rosa Therapeutics buyer in Q1 2025 was BVF Inc, an estimated $17.8M added.
  • The largest Monte Rosa Therapeutics seller in Q1 2025 was Morgan Stanley, an estimated $11.2M sold.

Based on aggregated 13F filings for Q1 2025.