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Monte Rosa Therapeutics

161 hedge funds and large institutions have $1.01B invested in Monte Rosa Therapeutics in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 54 increasing their positions, 39 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 16

127% more capital invested

Capital invested by funds: $445M → $1.01B (+$566M)

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

38% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 39

25% more funds holding

Funds holding: 129161 (+32)

1.8% more ownership

Funds ownership: 97.22%99.02% (+1.8%)

25% less call options, than puts

Call options by funds: $4.75M | Put options by funds: $6.37M

Holders
161
Holders Change
+32
Holders Change %
+24.81%
% of All Funds
1.96%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
49
Increased
54
Reduced
39
Closed
16
Calls
$4.75M
Puts
$6.37M
Net Calls
-$1.62M
Net Calls Change
+$437K
Name Holding Trade Value Shares
Change
Change in
Stake
LFG
151
Larson Financial Group
Missouri
$2.84K
TWD
152
True Wealth Design
Ohio
$1.74K +$364 +27 +32%
RIL
153
Rothschild Investment LLC
Illinois
$1.57K +$674 +50 +100%
Bessemer Group
154
Bessemer Group
New Jersey
$1K
SAM
155
Smartleaf Asset Management
Massachusetts
$591 +$499 +37 New
MCM
156
MAI Capital Management
Ohio
$518 +$445 +33 New
SIC
157
SJS Investment Consulting
Ohio
$455 +$391 +29 New
CIAM
158
Caitong International Asset Management
Hong Kong
$423 +$364 +27 New
TPBG
159
Turning Point Benefit Group
Maryland
$219
CA
160
Clearstead Advisors
Ohio
$126 -$364 -27 -77%
SS
161
Sunbelt Securities
Texas
$16 +$13 +1 New
Balyasny Asset Management
162
Balyasny Asset Management
Illinois
-$3.03M -408,540 Closed
Renaissance Technologies
163
Renaissance Technologies
New York
-$2.93M -395,733 Closed
Macquarie Group
164
Macquarie Group
Australia
-$1.48M -200,000 Closed
JC
165
JBF Capital
Colorado
-$1.1M -148,566 Closed
Qube Research & Technologies (QRT)
166
Qube Research & Technologies (QRT)
United Kingdom
-$1.09M -147,726 Closed
Point72 Asset Management
167
Point72 Asset Management
Connecticut
-$670K -90,419 Closed
Mackenzie Financial
168
Mackenzie Financial
Ontario, Canada
-$575K -77,635 Closed
OAC
169
OMERS Administration Corp
Ontario, Canada
-$210K -28,300 Closed
B
170
Bailard
California
-$167K -22,500 Closed
SRL
171
Scientech Research LLC
New Jersey
-$120K -16,254 Closed
Prudential Financial
172
Prudential Financial
New Jersey
-$89.3K -12,054 Closed
Two Sigma Advisers
173
Two Sigma Advisers
New York
-$82.3K -11,100 Closed
RA
174
Royce & Associates
New York
-$81.7K -11,024 Closed
EGM
175
Engineers Gate Manager
New York
-$80.6K -10,871 Closed