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Monte Rosa Therapeutics

161 hedge funds and large institutions have $1.01B invested in Monte Rosa Therapeutics in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 54 increasing their positions, 39 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 16

127% more capital invested

Capital invested by funds: $445M → $1.01B (+$566M)

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

38% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 39

25% more funds holding

Funds holding: 129161 (+32)

1.8% more ownership

Funds ownership: 97.22%99.02% (+1.8%)

25% less call options, than puts

Call options by funds: $4.75M | Put options by funds: $6.37M

Holders
161
Holders Change
+32
Holders Change %
+24.81%
% of All Funds
1.96%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
49
Increased
54
Reduced
39
Closed
16
Calls
$4.75M
Puts
$6.37M
Net Calls
-$1.62M
Net Calls Change
+$437K
Name Holding Trade Value Shares
Change
Change in
Stake
Charles Schwab
26
Charles Schwab
California
$7.04M +$882K +65,446 +17%
Marshall Wace
27
Marshall Wace
United Kingdom
$6.25M -$6.79M -503,944 -56%
Invesco
28
Invesco
Georgia
$5.68M +$3.56M +264,315 +270%
Arrowstreet Capital
29
Arrowstreet Capital
Massachusetts
$4.82M +$4.15M +307,651 New
Goldman Sachs
30
Goldman Sachs
New York
$4.64M +$2.62M +194,734 +193%
N
31
Nuveen
North Carolina
$4.48M +$2.46M +182,891 +178%
NI
32
Nextech Invest
Switzerland
$4.38M +$3.76M +279,237 New
EF
33
Empowered Funds
Pennsylvania
$4.36M +$2.57M +190,627 +218%
Acadian Asset Management
34
Acadian Asset Management
Massachusetts
$3.88M +$597K +44,305 +22%
Bank of America
35
Bank of America
North Carolina
$3.51M -$621K -46,072 -17%
ACM
36
ADAR1 Capital Management
Texas
$3.38M
TD Asset Management
37
TD Asset Management
Ontario, Canada
$3.35M +$558K +41,386 +24%
NAMI
38
Nomura Asset Management International
Pennsylvania
$3.14M +$2.7M +200,000 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$2.72M -$182K -13,494 -7%
TI
40
Trexquant Investment
Connecticut
$2.35M +$2.02M +149,712 New
Wellington Management Group
41
Wellington Management Group
Massachusetts
$2.32M -$141K -10,467 -7%
AI
42
Atom Investors
Texas
$2.15M +$1.85M +137,261 New
Jane Street
43
Jane Street
New York
$2.15M -$2.29M -170,000 -55%
Manulife (Manufacturers Life Insurance)
44
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.15M +$220K +16,291 +14%
Barclays
45
Barclays
United Kingdom
$2.13M +$849K +63,029 +86%
UBS Group
46
UBS Group
Switzerland
$1.93M +$686K +50,905 +71%
Ameriprise
47
Ameriprise
Minnesota
$1.92M +$1.65M +122,164 New
Millennium Management
48
Millennium Management
New York
$1.63M -$4.59M -340,967 -77%
CCIA
49
Campbell & Co Investment Adviser
Maryland
$1.42M +$534K +39,619 +77%
IC
50
IEQ Capital
California
$1.4M +$407K +30,202 +51%