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Monte Rosa Therapeutics

116 hedge funds and large institutions have $281M invested in Monte Rosa Therapeutics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 50 increasing their positions, 17 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,510% more call options, than puts

Call options by funds: $483K | Put options by funds: $30K

194% more repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 17

65% more first-time investments, than exits

New positions opened: 28 | Existing positions closed: 17

10% more funds holding

Funds holding: 105116 (+11)

4.37% more ownership

Funds ownership: 96.77%101.14% (+4.4%)

2% more capital invested

Capital invested by funds: $276M → $281M (+$4.38M)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

Holders
116
Holders Change
+11
Holders Change %
+10.48%
% of All Funds
1.53%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
28
Increased
50
Reduced
17
Closed
17
Calls
$483K
Puts
$30K
Net Calls
+$453K
Net Calls Change
+$246K
Name Holding Trade Value Shares
Change
Change in
Stake
GCP
26
GSA Capital Partners
United Kingdom
$1.28M +$1.2M +268,650 +1,772%
BCM
27
Bridgeway Capital Management
Texas
$1.22M +$1.21M +271,400 New
Bank of America
28
Bank of America
North Carolina
$1.22M +$1.09M +245,119 +941%
Two Sigma Investments
29
Two Sigma Investments
New York
$1.08M +$75K +16,807 +8%
Wellington Management Group
30
Wellington Management Group
Massachusetts
$1.01M +$165K +37,087 +20%
Qube Research & Technologies (QRT)
31
Qube Research & Technologies (QRT)
United Kingdom
$917K +$690K +154,722 +318%
Squarepoint
32
Squarepoint
New York
$803K +$795K +178,136 New
Bank of New York Mellon
33
Bank of New York Mellon
New York
$791K +$49.9K +11,198 +7%
TD Asset Management
34
TD Asset Management
Ontario, Canada
$776K
Manulife (Manufacturers Life Insurance)
35
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$540K +$11.3K +2,529 +2%
ECM
36
ExodusPoint Capital Management
New York
$493K +$57.5K +12,882 +13%
UBS Group
37
UBS Group
Switzerland
$488K +$74.6K +16,727 +18%
N
38
Nuveen
North Carolina
$464K -$65.6K -14,704 -12%
CC
39
Casdin Capital
New York
$388K
Barclays
40
Barclays
United Kingdom
$387K +$176K +39,502 +85%
Franklin Resources
41
Franklin Resources
California
$381K +$257K +57,539 +214%
Citadel Advisors
42
Citadel Advisors
Florida
$351K +$348K +77,918 New
Mackenzie Financial
43
Mackenzie Financial
Ontario, Canada
$350K +$346K +77,635 New
IC
44
IEQ Capital
California
$334K +$330K +73,975 New
Two Sigma Advisers
45
Two Sigma Advisers
New York
$327K +$323K +72,500 New
Invesco
46
Invesco
Georgia
$295K +$134K +30,043 +85%
Millennium Management
47
Millennium Management
New York
$291K -$1.19M -265,836 -80%
RhumbLine Advisers
48
RhumbLine Advisers
Massachusetts
$287K +$6K +1,346 +2%
AllianceBernstein
49
AllianceBernstein
Tennessee
$286K +$126K +28,340 +81%
HIM
50
Hillsdale Investment Management
Ontario, Canada
$271K +$268K +60,100 New

GLUE Hedge Fund Activity: Q2 2025 in Review

116 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Monte Rosa Therapeutics (GLUE) for Q2 2025, worth a combined $281M — up 1.6% from $276M a quarter earlier.

Buyers outnumbered sellers: 28 funds opened new GLUE positions and 17 closed out — a net gain of 11 holders — while 50 added to existing stakes and 17 trimmed.

The largest buyer was Suvretta Capital Management, adding an estimated $8.01M. The largest seller was Fidelity Investments, cutting an estimated $10.6M.

  • 116 institutional investors held Monte Rosa Therapeutics (GLUE) as of Q2 2025, up from 105 in Q1 2025.
  • Funds reported $281M of Monte Rosa Therapeutics stock for Q2 2025, up 1.6% quarter-over-quarter.
  • 28 funds opened new Monte Rosa Therapeutics positions in Q2 2025 and 17 closed out, a net change of +11 holders.
  • The largest Monte Rosa Therapeutics buyer in Q2 2025 was Suvretta Capital Management, an estimated $8.01M added.
  • The largest Monte Rosa Therapeutics seller in Q2 2025 was Fidelity Investments, an estimated $10.6M sold.

Based on aggregated 13F filings for Q2 2025.