|
1
|
RA Capital Management
Boston,
Massachusetts
|
$47.9M
|
–
|
–
|
–
|
|
|
2
|
|
$39.8M
|
+$794K
|
+435,807
|
+2%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$30.1M
|
-$530K
|
-290,844
|
-2%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$25.7M
|
+$833K
|
+457,302
|
+3%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$21.6M
|
+$3.48M
|
+1,909,521
|
+16%
|
|
|
6
|
NEA Management Company
Timonium,
Maryland
|
$21.4M
|
–
|
–
|
–
|
|
|
7
|
Perceptive Advisors
New York
|
$21.4M
|
–
|
–
|
–
|
|
|
8
|
Great Point Partners
Greenwich,
Connecticut
|
$8.04M
|
-$8.44M
|
-4,630,339
|
-48%
|
|
|
9
|
Nuveen
Charlotte,
North Carolina
|
$7.84M
|
-$67
|
-37
|
-0%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$7.25M
|
+$20.3K
|
+11,125
|
+0.2%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$6.54M
|
-$1.36M
|
-747,947
|
-15%
|
|
|
12
|
Northern Trust
Chicago,
Illinois
|
$5.12M
|
-$203K
|
-111,326
|
-3%
|
|
|
13
|
Millennium Management
New York
|
$4.96M
|
+$4.31M
|
+2,366,468
|
+315%
|
|
|
14
|
Two Sigma Advisers
New York
|
$3.24M
|
+$1.84M
|
+1,008,500
|
+98%
|
|
|
15
|
Charles Schwab
San Francisco,
California
|
$3.2M
|
+$5.26K
|
+2,886
|
+0.1%
|
|
|
16
|
Two Sigma Investments
New York
|
$2.52M
|
+$557K
|
+305,895
|
+24%
|
|
|
17
|
Bank of New York Mellon
New York
|
$1.96M
|
+$180K
|
+98,632
|
+9%
|
|
|
18
|
Samsara BioCapital
Palo Alto,
California
|
$1.95M
|
-$558K
|
-306,218
|
-20%
|
|
|
19
|
|
$1.63M
|
+$1.24M
|
+678,468
|
+197%
|
|
|
20
|
|
$1.59M
|
+$1.64M
|
+900,025
|
+885%
|
|
|
21
|
Renaissance Technologies
New York
|
$1.56M
|
+$1.75M
|
+961,624
|
+4,606%
|
|
|
22
|
Swiss National Bank
Zurich,
Switzerland
|
$1.12M
|
–
|
–
|
–
|
|
|
23
|
California Public Employees Retirement System
Sacramento,
California
|
$1.01M
|
-$22.2K
|
-12,200
|
-2%
|
|
|
24
|
Credit Suisse
Zurich,
Switzerland
|
$939K
|
+$6.75K
|
+3,707
|
+0.6%
|
|
|
25
|
Wells Fargo
San Francisco,
California
|
$916K
|
+$810K
|
+444,536
|
+335%
|
|
