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Gain Therapeutics

48 hedge funds and large institutions have $25.9M invested in Gain Therapeutics in 2025 Q4 according to their latest regulatory filings, with 21 funds opening new positions, 15 increasing their positions, 3 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

400% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 3

237% more capital invested

Capital invested by funds: $7.7M → $25.9M (+$18.2M)

157% more call options, than puts

Call options by funds: $375K | Put options by funds: $146K

110% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 10

26% more funds holding

Funds holding: 3848 (+10)

8.87% more ownership

Funds ownership: 12.08%20.95% (+8.9%)

Holders
48
Holders Change
+10
Holders Change %
+26.32%
% of All Funds
0.58%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
21
Increased
15
Reduced
3
Closed
10
Calls
$375K
Puts
$146K
Net Calls
+$229K
Net Calls Change
+$60K
Name Holding Trade Value Shares
Change
Change in
Stake
Marshall Wace
1
Marshall Wace
United Kingdom
$5.35M +$3.97M +1,487,186 +849%
PCM
2
Potomac Capital Management
New York
$3.25M +$2.7M +1,010,000 New
Jones Financial Companies
3
Jones Financial Companies
Missouri
$2.26M +$67.8K +25,391 +4%
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$2.2M +$1.61M +603,914 +751%
Vanguard Group
5
Vanguard Group
Pennsylvania
$1.84M +$94.9K +35,549 +7%
Cambridge Investment Research Advisors
6
Cambridge Investment Research Advisors
Iowa
$1.83M +$667K +250,000 +78%
DCM
7
DME Capital Management
New York
$1.82M
Geode Capital Management
8
Geode Capital Management
Massachusetts
$1.28M +$144K +53,796 +16%
Jane Street
9
Jane Street
New York
$780K +$453K +169,878 +234%
BlackRock
10
BlackRock
New York
$675K +$249K +93,395 +80%
CAM
11
Cresset Asset Management
Illinois
$515K +$427K +160,000 New
State Street
12
State Street
Massachusetts
$507K +$177K +66,400 +73%
Morgan Stanley
13
Morgan Stanley
New York
$475K -$21.6K -8,084 -5%
LPL Financial
14
LPL Financial
California
$343K +$284K +106,550 New
Northern Trust
15
Northern Trust
Illinois
$328K +$36.3K +13,602 +15%
UBS Group
16
UBS Group
Switzerland
$261K -$159K -59,556 -42%
Focus Partners Wealth
17
Focus Partners Wealth
Massachusetts
$251K +$208K +77,855 New
HF
18
HRT Financial
New York
$179K +$96K +35,962 +182%
Group One Trading
19
Group One Trading
Illinois
$174K +$99.8K +37,384 +223%
Simplex Trading
20
Simplex Trading
Illinois
$154K +$128K +47,946 New
BFA
21
Benedict Financial Advisors
Georgia
$122K +$8.01K +3,000 +9%
OAC
22
OMERS Administration Corp
Ontario, Canada
$120K +$99.5K +37,300 New
PCM
23
Prelude Capital Management
New York
$115K
Goldman Sachs
24
Goldman Sachs
New York
$105K +$86.7K +32,494 New
Point72 Asset Management
25
Point72 Asset Management
Connecticut
$105K +$86.7K +32,480 New

GANX Hedge Fund Activity: Q4 2025 in Review

48 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Gain Therapeutics (GANX) for Q4 2025, worth a combined $25.9M — up 237% from $7.7M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new GANX positions and 10 closed out — a net gain of 11 holders — while 15 added to existing stakes and 3 trimmed.

The largest buyer was Marshall Wace, adding an estimated $3.97M. The largest seller was Citadel Advisors, exiting entirely with an estimated $997K sold.

  • 48 institutional investors held Gain Therapeutics (GANX) as of Q4 2025, up from 38 in Q3 2025.
  • Funds reported $25.9M of Gain Therapeutics stock for Q4 2025, up 237% quarter-over-quarter.
  • 21 funds opened new Gain Therapeutics positions in Q4 2025 and 10 closed out, a net change of +11 holders.
  • The largest Gain Therapeutics buyer in Q4 2025 was Marshall Wace, an estimated $3.97M added.
  • The largest Gain Therapeutics seller in Q4 2025 was Citadel Advisors, an estimated $997K sold.

Based on aggregated 13F filings for Q4 2025.