|
1
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
–
|
-$230M
|
-10,811,153
|
Closed
|
|
|
2
|
Perceptive Advisors
New York
|
–
|
-$146M
|
-6,825,395
|
Closed
|
|
|
3
|
Avidity Partners Management
Dallas,
Texas
|
–
|
-$139M
|
-6,500,328
|
Closed
|
|
|
4
|
Deerfield Management
New York
|
–
|
-$136M
|
-6,401,000
|
Closed
|
|
|
5
|
Fidelity International
Hamilton,
Bermuda
|
–
|
-$89.3M
|
-4,187,271
|
Closed
|
|
|
6
|
Pentwater Capital Management
Naples,
Florida
|
–
|
-$80.6M
|
-3,781,778
|
Closed
|
|
|
7
|
Johnson & Johnson
New Brunswick,
New Jersey
|
–
|
-$78.3M
|
-3,670,516
|
Closed
|
|
|
8
|
Canada Pension Plan Investment Board
Toronto Ontario,
Ontario, Canada
|
–
|
-$66.5M
|
-3,116,966
|
Closed
|
|
|
9
|
TPG GP A
Fort Worth,
Texas
|
–
|
-$54.4M
|
-2,551,794
|
Closed
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$39.2M
|
-1,836,739
|
Closed
|
|
|
11
|
Millennium Management
New York
|
–
|
-$34.3M
|
-1,608,882
|
Closed
|
|
|
12
|
Marshall Wace
London,
United Kingdom
|
–
|
-$32M
|
-1,501,283
|
Closed
|
|
|
13
|
TIG Advisors LLC
New York
|
–
|
-$21.4M
|
-1,003,628
|
Closed
|
|
|
14
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
–
|
-$21M
|
-987,178
|
Closed
|
|
|
15
|
William Blair & Company
Chicago,
Illinois
|
–
|
-$16.6M
|
-779,202
|
Closed
|
|
|
16
|
1832 Asset Management
Toronto,
Ontario, Canada
|
–
|
-$15.7M
|
-734,321
|
Closed
|
|
|
17
|
|
–
|
-$14M
|
-657,385
|
Closed
|
|
|
18
|
|
–
|
-$13.5M
|
-633,932
|
Closed
|
|
|
19
|
|
–
|
-$12.9M
|
-605,742
|
Closed
|
|
|
20
|
Alpine Associates Management
Palm Beach,
Florida
|
–
|
-$12.5M
|
-585,102
|
Closed
|
|
|
21
|
Eagle Health Investments
Greenwich,
Connecticut
|
–
|
-$12.4M
|
-579,769
|
Closed
|
|
|
22
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
–
|
-$12M
|
-563,385
|
Closed
|
|
|
23
|
|
–
|
-$11M
|
-516,795
|
Closed
|
|
|
24
|
Sand Grove Capital Management
London,
United Kingdom
|
–
|
-$10.5M
|
-490,547
|
Closed
|
|
|
25
|
Balyasny Asset Management
Chicago,
Illinois
|
–
|
-$10.4M
|
-486,971
|
Closed
|
|
