|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$232M
|
+$9.22M
|
+573,813
|
+11%
|
|
|
2
|
|
$150M
|
–
|
–
|
–
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$109M
|
+$18.4M
|
+1,143,344
|
+70%
|
|
|
4
|
|
$83.3M
|
+$3.51M
|
+218,232
|
+12%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$76.1M
|
+$31.1M
|
+1,933,250
|
New
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$64.5M
|
+$6.83M
|
+425,320
|
+35%
|
|
|
7
|
Alphabet Inc
Mountain View,
California
|
$40.6M
|
-$8.28M
|
-515,322
|
-33%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$35.5M
|
+$6.47M
|
+402,670
|
+81%
|
|
|
9
|
Board of Trustees of The Leland Stanford Junior University
Redwood City,
California
|
$27.7M
|
–
|
–
|
–
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$25.7M
|
-$3.43M
|
-213,738
|
-25%
|
|
|
11
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$25.1M
|
+$10.2M
|
+637,563
|
New
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$23.4M
|
+$7.7M
|
+479,359
|
+419%
|
|
|
13
|
Opaleye Management
Boston,
Massachusetts
|
$22.1M
|
+$2.2M
|
+137,000
|
+32%
|
|
|
14
|
VHCP Management III
New York
|
$20.3M
|
+$8.29M
|
+516,381
|
New
|
|
|
15
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$19M
|
+$7.73M
|
+481,432
|
New
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$17.7M
|
+$7.23M
|
+450,000
|
New
|
|
|
17
|
Deerfield Management
New York
|
$17.6M
|
-$4.87M
|
-303,000
|
-40%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$16.8M
|
+$1.82M
|
+113,449
|
+36%
|
|
|
19
|
Millennium Management
New York
|
$16.1M
|
+$6.59M
|
+410,099
|
New
|
|
|
20
|
Duquesne Family Office
New York
|
$15.2M
|
+$6.18M
|
+385,026
|
New
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$14.8M
|
+$1.52M
|
+94,704
|
+34%
|
|
|
22
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$12.5M
|
+$1.49K
|
+93
|
+0%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$11.8M
|
+$484K
|
+30,153
|
+11%
|
|
|
24
|
|
$10.8M
|
+$4.4M
|
+273,750
|
New
|
|
|
25
|
Bourgeon Capital Management
Darien,
Connecticut
|
$8.9M
|
-$1.52M
|
-94,499
|
-29%
|
|