Amicus Therapeutics
FOLD
FOLD was delisted on the 24th of April, 2026.
224 hedge funds and large institutions have $3.48B invested in Amicus Therapeutics in 2021 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 74 increasing their positions, 80 reducing their positions, and 37 closing their positions.
147% more call options, than puts
Call options by funds: $9.67M | Put options by funds: $3.91M
24% more capital invested
Capital invested by funds: $2.8B → $3.48B (+$680M)
17% more funds holding in top 10
Funds holding in top 10: 6 → 7 (+1)
8% less repeat investments, than reductions
Existing positions increased: 74 | Existing positions reduced: 80
1.68% less ownership
Funds ownership: 109.87% → 108.19% (-1.7%)
5% less funds holding
Funds holding: 237 → 224 (-13)
30% less first-time investments, than exits
New positions opened: 26 | Existing positions closed: 37
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Janus Henderson Group
London,
United Kingdom
|
+$31.2M |
| 2 |
Wellington Management Group
Boston,
Massachusetts
|
+$26.2M |
| 3 |
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
+$23M |
| 4 |
Morgan Stanley
New York
|
+$21.8M |
| 5 |
RG
Redmile Group
San Francisco,
California
|
+$21.4M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
-$15M |
| 2 |
Citadel Advisors
Miami,
Florida
|
-$14.5M |
| 3 |
SAM
Sectoral Asset Management
Montreal,
Quebec, Canada
|
-$13M |
| 4 |
Goldman Sachs
New York
|
-$8.81M |
| 5 |
Massachusetts Financial Services
Boston,
Massachusetts
|
-$8.47M |
FOLD Hedge Fund Activity: Q4 2021 in Review
224 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in Amicus Therapeutics (FOLD) for Q4 2021, worth a combined $3.48B — up 24% from $2.8B a quarter earlier.
Sellers outnumbered buyers: 37 funds closed out of FOLD and 26 opened new positions — a net loss of 11 holders — while 80 trimmed existing stakes and 74 added.
The largest buyer was Janus Henderson Group, adding an estimated $31.2M. The largest seller was Deutsche Bank, cutting an estimated $15M.
- 224 institutional investors held Amicus Therapeutics (FOLD) as of Q4 2021, down from 237 in Q3 2021.
- Funds reported $3.48B of Amicus Therapeutics stock for Q4 2021, up 24% quarter-over-quarter.
- 26 funds opened new Amicus Therapeutics positions in Q4 2021 and 37 closed out, a net change of -11 holders.
- The largest Amicus Therapeutics buyer in Q4 2021 was Janus Henderson Group, an estimated $31.2M added.
- The largest Amicus Therapeutics seller in Q4 2021 was Deutsche Bank, an estimated $15M sold.
Based on aggregated 13F filings for Q4 2021.