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Foghorn Therapeutics
FHTX

93 hedge funds and large institutions have $226M invested in Foghorn Therapeutics in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 31 increasing their positions, 24 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 10

29% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 24

13% more capital invested

Capital invested by funds: $200M → $226M (+$25.9M)

6% more funds holding

Funds holding: 88 → 93 (+5)

1.7% more ownership

Funds ownership: 72.35% → 74.05% (+1.7%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

75% less call options, than puts

Call options by funds: $1K | Put options by funds: $4K

Holders
93
Holders Change
+5
Holders Change %
+5.68%
% of All Funds
1.13%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
15
Increased
31
Reduced
24
Closed
10
Calls
$1K
Puts
$4K
Net Calls
-$3K
Net Calls Change
-$5K

Top Buyers

Rank Fund Capital Flow
1
Ameriprise
Ameriprise
Minnesota
+$2.75M
2
DM
Deerfield Management
New York
+$1.78M
3
Renaissance Technologies
Renaissance Technologies
New York
+$814K
4
Citadel Advisors
Citadel Advisors
Florida
+$772K
5
Squarepoint
Squarepoint
New York
+$476K

Top Sellers

Rank Fund Capital Flow
1
AI
Alphabet Inc
California
-$2.45M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$1.4M
3
RAM
Readystate Asset Management
Illinois
-$788K
4
WP
Woodline Partners
California
-$395K
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$352K
Name Holding Trade Value Shares
Change 		Change in
Stake
FP
1
Flagship Pioneering
Massachusetts
$68.4M – – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$29.1M -$352K -77,677 -1%
BI
3
BVF Inc
California
$28.6M – – –
DM
4
Deerfield Management
New York
$19.7M +$1.78M +393,697 +12%
Raymond James Financial
5
Raymond James Financial
Florida
$13.5M +$196K +43,333 +2%
BlackRock
6
BlackRock
New York
$12.7M +$408K +89,922 +4%
Vanguard Group
7
Vanguard Group
Pennsylvania
$10.4M +$134K +29,535 +2%
EC
8
Euclidean Capital
New York
$8.5M – – –
Geode Capital Management
9
Geode Capital Management
Massachusetts
$4.29M -$61K -13,448 -2%
SL
10
Siren LLC
Connecticut
$3.89M – – –
State Street
11
State Street
Massachusetts
$3.34M -$83.8K -18,482 -3%
Ameriprise
12
Ameriprise
Minnesota
$3.28M +$2.75M +607,670 New
Renaissance Technologies
13
Renaissance Technologies
New York
$1.61M +$814K +179,500 +152%
BC
14
Birchview Capital
Vermont
$1.52M – – –
Jacobs Levy Equity Management
15
Jacobs Levy Equity Management
New Jersey
$1.45M +$386K +85,123 +46%
Northern Trust
16
Northern Trust
Illinois
$1.42M -$99.2K -21,871 -8%
Millennium Management
17
Millennium Management
New York
$1.13M +$135K +29,774 +17%
Citadel Advisors
18
Citadel Advisors
Florida
$984K +$772K +170,249 +1,416%
Squarepoint
19
Squarepoint
New York
$765K +$476K +104,968 +287%
Jane Street
20
Jane Street
New York
$716K +$300K +66,112 +100%
DCM
21
DAFNA Capital Management
California
$685K – – –
SCM
22
Sio Capital Management
New York
$664K – – –
Morgan Stanley
23
Morgan Stanley
New York
$657K +$263K +58,051 +91%
Goldman Sachs
24
Goldman Sachs
New York
$641K +$210K +46,254 +64%
SCM
25
SCS Capital Management
Massachusetts
$578K – – –
1
2 3 4 5

FHTX Hedge Fund Activity: Q4 2025 in Review

93 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Foghorn Therapeutics (FHTX) for Q4 2025, worth a combined $226M — up 13% from $200M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new FHTX positions and 10 closed out — a net gain of 5 holders — while 31 added to existing stakes and 24 trimmed.

The largest buyer was Ameriprise, opening a new position worth an estimated $2.75M. The largest seller was Alphabet Inc, exiting entirely with an estimated $2.45M sold.

  • 93 institutional investors held Foghorn Therapeutics (FHTX) as of Q4 2025, up from 88 in Q3 2025.
  • Funds reported $226M of Foghorn Therapeutics stock for Q4 2025, up 13% quarter-over-quarter.
  • 15 funds opened new Foghorn Therapeutics positions in Q4 2025 and 10 closed out, a net change of +5 holders.
  • The largest Foghorn Therapeutics buyer in Q4 2025 was Ameriprise, an estimated $2.75M added.
  • The largest Foghorn Therapeutics seller in Q4 2025 was Alphabet Inc, an estimated $2.45M sold.

Based on aggregated 13F filings for Q4 2025.