Foghorn Therapeutics
FHTX
93 hedge funds and large institutions have $226M invested in Foghorn Therapeutics in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 31 increasing their positions, 24 reducing their positions, and 10 closing their positions.
50% more first-time investments, than exits
New positions opened: 15 | Existing positions closed: 10
29% more repeat investments, than reductions
Existing positions increased: 31 | Existing positions reduced: 24
13% more capital invested
Capital invested by funds: $200M → $226M (+$25.9M)
6% more funds holding
Funds holding: 88 → 93 (+5)
1.7% more ownership
Funds ownership: 72.35% → 74.05% (+1.7%)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
75% less call options, than puts
Call options by funds: $1K | Put options by funds: $4K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Ameriprise
Minneapolis,
Minnesota
|
+$2.75M |
| 2 |
DM
Deerfield Management
New York
|
+$1.78M |
| 3 |
Renaissance Technologies
New York
|
+$814K |
| 4 |
Citadel Advisors
Miami,
Florida
|
+$772K |
| 5 |
Squarepoint
New York
|
+$476K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
AI
Alphabet Inc
Mountain View,
California
|
-$2.45M |
| 2 |
Point72 Asset Management
Stamford,
Connecticut
|
-$1.4M |
| 3 |
RAM
Readystate Asset Management
Chicago,
Illinois
|
-$788K |
| 4 |
WP
Woodline Partners
San Francisco,
California
|
-$395K |
| 5 |
Fidelity Investments
Boston,
Massachusetts
|
-$352K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
AAP
101
Arax Advisory Partners
Denver,
Colorado
| – | -$2.54K | -519 | Closed |
|
102
Group One Trading
Chicago,
Illinois
| – | -$2.21K | -451 | Closed |
|
|
EP
103
Essential Partners
Rancho Santa Fe,
California
| – | -$24 | -5 | Closed |
|
FHTX Hedge Fund Activity: Q4 2025 in Review
93 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Foghorn Therapeutics (FHTX) for Q4 2025, worth a combined $226M — up 13% from $200M a quarter earlier.
Buyers outnumbered sellers: 15 funds opened new FHTX positions and 10 closed out — a net gain of 5 holders — while 31 added to existing stakes and 24 trimmed.
The largest buyer was Ameriprise, opening a new position worth an estimated $2.75M. The largest seller was Alphabet Inc, exiting entirely with an estimated $2.45M sold.
- 93 institutional investors held Foghorn Therapeutics (FHTX) as of Q4 2025, up from 88 in Q3 2025.
- Funds reported $226M of Foghorn Therapeutics stock for Q4 2025, up 13% quarter-over-quarter.
- 15 funds opened new Foghorn Therapeutics positions in Q4 2025 and 10 closed out, a net change of +5 holders.
- The largest Foghorn Therapeutics buyer in Q4 2025 was Ameriprise, an estimated $2.75M added.
- The largest Foghorn Therapeutics seller in Q4 2025 was Alphabet Inc, an estimated $2.45M sold.
Based on aggregated 13F filings for Q4 2025.