|
1
|
RA Capital Management
Boston,
Massachusetts
|
$161M
|
+$22.7M
|
+888,300
|
+21%
|
|
|
2
|
|
$140M
|
+$24.9M
|
+975,969
|
+29%
|
|
|
3
|
|
$137M
|
+$20.9M
|
+819,961
|
+24%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$125M
|
-$2.17M
|
-85,000
|
-2%
|
|
|
5
|
Janus Henderson Group
London,
|
$102M
|
+$2.66M
|
+104,148
|
+3%
|
|
|
6
|
|
$97.4M
|
+$57.2M
|
+2,241,506
|
+275%
|
|
|
7
|
Deep Track Capital
Greenwich,
Connecticut
|
$96.7M
|
+$19.1M
|
+750,081
|
+33%
|
|
|
8
|
Viking Global Investors
Stamford,
Connecticut
|
$93.5M
|
-$47.3M
|
-1,853,000
|
-39%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$74.6M
|
+$12.1M
|
+473,094
|
+25%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$69.4M
|
+$16.7M
|
+654,240
|
+43%
|
|
|
11
|
Polar Capital Holdings
London,
United Kingdom
|
$57.3M
|
+$45.9M
|
+1,798,492
|
New
|
|
|
12
|
|
$49.4M
|
-$486K
|
-19,058
|
-1%
|
|
|
13
|
Novo Holdings A/S
Hellerup,
Denmark
|
$44.6M
|
-$2.55M
|
-100,000
|
-7%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$40.2M
|
+$32.2M
|
+1,261,427
|
New
|
|
|
15
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$34.4M
|
-$3.14M
|
-123,115
|
-10%
|
|
|
16
|
Braidwell
Stamford,
Connecticut
|
$33.5M
|
+$26.9M
|
+1,052,485
|
New
|
|
|
17
|
Fidelity Investments
Boston,
Massachusetts
|
$30.9M
|
+$24.6M
|
+965,245
|
+26,540%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$27.8M
|
+$2.41M
|
+94,501
|
+12%
|
|
|
19
|
|
$25.5M
|
-$5.97M
|
-233,811
|
-23%
|
|
|
20
|
Eventide Asset Management
Boston,
Massachusetts
|
$24.7M
|
+$19.8M
|
+776,114
|
New
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$23.9M
|
+$1.38M
|
+54,099
|
+8%
|
|
|
22
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$20.4M
|
+$15M
|
+586,500
|
+1,076%
|
|
|
23
|
LMR Partners
London,
United Kingdom
|
$15.5M
|
+$12.4M
|
+487,533
|
New
|
|
|
24
|
Eagle Health Investments
Greenwich,
Connecticut
|
$14.7M
|
+$638K
|
+25,000
|
+6%
|
|
|
25
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$13.7M
|
+$11M
|
+430,556
|
New
|
|
