Exelixis
EXEL
685 hedge funds and large institutions have $11.4B invested in Exelixis in 2025 Q4 according to their latest regulatory filings, with 131 funds opening new positions, 232 increasing their positions, 243 reducing their positions, and 59 closing their positions.
122% more first-time investments, than exits
New positions opened: 131 | Existing positions closed: 59
50% more call options, than puts
Call options by funds: $58.9M | Put options by funds: $39.2M
10% more funds holding
Funds holding: 621 → 685 (+64)
10% more capital invested
Capital invested by funds: $10.4B → $11.4B (+$1.06B)
9% more funds holding in top 10
Funds holding in top 10: 11 → 12 (+1)
4.02% more ownership
Funds ownership: 93.11% → 97.13% (+4%)
5% less repeat investments, than reductions
Existing positions increased: 232 | Existing positions reduced: 243
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
AQR Capital Management
Greenwich,
Connecticut
|
+$185M |
| 2 |
D.E. Shaw & Co
New York
|
+$67.6M |
| 3 |
Thrivent Financial for Lutherans
Minneapolis,
Minnesota
|
+$46.6M |
| 4 |
Goldman Sachs
New York
|
+$46.1M |
| 5 |
UBS Group
Zurich,
Switzerland
|
+$44.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
FCM
Farallon Capital Management
San Francisco,
California
|
-$157M |
| 2 |
Renaissance Technologies
New York
|
-$63.9M |
| 3 |
Allianz Asset Management
Munich,
Germany
|
-$41.5M |
| 4 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$37.9M |
| 5 |
State Street
Boston,
Massachusetts
|
-$25.8M |
EXEL Hedge Fund Activity: Q4 2025 in Review
685 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Exelixis (EXEL) for Q4 2025, worth a combined $11.4B — up 10% from $10.4B a quarter earlier.
Buyers outnumbered sellers: 131 funds opened new EXEL positions and 59 closed out — a net gain of 72 holders — while 232 added to existing stakes and 243 trimmed.
The largest buyer was AQR Capital Management, adding an estimated $185M. The largest seller was Farallon Capital Management, cutting an estimated $157M.
- 685 institutional investors held Exelixis (EXEL) as of Q4 2025, up from 621 in Q3 2025.
- Funds reported $11.4B of Exelixis stock for Q4 2025, up 10% quarter-over-quarter.
- 131 funds opened new Exelixis positions in Q4 2025 and 59 closed out, a net change of +72 holders.
- The largest Exelixis buyer in Q4 2025 was AQR Capital Management, an estimated $185M added.
- The largest Exelixis seller in Q4 2025 was Farallon Capital Management, an estimated $157M sold.
Based on aggregated 13F filings for Q4 2025.