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Exelixis

633 hedge funds and large institutions have $11.2B invested in Exelixis in 2025 Q2 according to their latest regulatory filings, with 124 funds opening new positions, 235 increasing their positions, 214 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

195% more first-time investments, than exits

New positions opened: 124 | Existing positions closed: 42

20% more capital invested

Capital invested by funds: $9.38B → $11.2B (+$1.85B)

14% more funds holding

Funds holding: 557633 (+76)

2.64% more ownership

Funds ownership: 90.86%93.5% (+2.6%)

10% more repeat investments, than reductions

Existing positions increased: 235 | Existing positions reduced: 214

7% more call options, than puts

Call options by funds: $82.8M | Put options by funds: $77.6M

0% more funds holding in top 10

Funds holding in top 10: 1010 (0)

Holders
633
Holders Change
+76
Holders Change %
+13.64%
% of All Funds
8.33%
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.13%
New
124
Increased
235
Reduced
214
Closed
42
Calls
$82.8M
Puts
$77.6M
Net Calls
+$5.2M
Net Calls Change
-$38M
Name Holding Trade Value Shares
Change
Change in
Stake
IIM
76
INTECH Investment Management
Florida
$19.9M +$2.37M +59,306 +15%
DekaBank Deutsche Girozentrale
77
DekaBank Deutsche Girozentrale
Germany
$19.2M
Two Sigma Advisers
78
Two Sigma Advisers
New York
$18.9M -$74.2M -1,856,300 -81%
EF
79
Empowered Funds
Pennsylvania
$18.8M +$4.99M +124,723 +41%
Massachusetts Financial Services
80
Massachusetts Financial Services
Massachusetts
$18.7M +$3.41M +85,348 +25%
DCM
81
Driehaus Capital Management
Illinois
$18.7M -$1.6M -40,094 -9%
IC
82
IEQ Capital
California
$17.9M +$2.84M +71,108 +21%
BC
83
Burney Company
Virginia
$17.9M +$196K +4,912 +1%
PAM
84
Panagora Asset Management
Massachusetts
$17.8M +$15.2M +379,309 +1,615%
Axa
85
Axa
France
$17.2M +$6.93M +173,303 +80%
Pictet Asset Management
86
Pictet Asset Management
Switzerland
$16.7M -$7.28M -182,021 -32%
MPM
87
Meritage Portfolio Management
Kansas
$16.6M -$860K -21,511 -5%
AllianceBernstein
88
AllianceBernstein
Tennessee
$16.2M -$356K -8,914 -2%
New York State Teachers Retirement System (NYSTRS)
89
New York State Teachers Retirement System (NYSTRS)
New York
$15.7M -$85.3K -2,133 -0.6%
VOYA Investment Management
90
VOYA Investment Management
Georgia
$15.6M +$1.1M +27,478 +8%
SCP
91
Seizert Capital Partners
Michigan
$15.3M -$1.22M -30,439 -8%
Victory Capital Management
92
Victory Capital Management
Texas
$15M -$160K -3,991 -1%
Acadian Asset Management
93
Acadian Asset Management
Massachusetts
$15M -$60.8M -1,520,175 -82%
State Board of Administration of Florida Retirement System
94
State Board of Administration of Florida Retirement System
Florida
$14.8M -$477K -11,923 -3%
Macquarie Group
95
Macquarie Group
Australia
$14.1M +$5.49M +137,469 +76%
HW
96
Hancock Whitney
Mississippi
$12.9M +$9.67M +241,841 +479%
Capital Fund Management (CFM)
97
Capital Fund Management (CFM)
France
$12.5M +$706K +17,673 +7%
ECM
98
ExodusPoint Capital Management
New York
$12.4M +$11.3M +281,556 New
William Blair & Company
99
William Blair & Company
Illinois
$12.1M -$723K -18,091 -6%
Envestnet Asset Management
100
Envestnet Asset Management
Illinois
$12M +$945K +23,644 +10%

EXEL Hedge Fund Activity: Q2 2025 in Review

633 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Exelixis (EXEL) for Q2 2025, worth a combined $11.2B — up 20% from $9.38B a quarter earlier.

Buyers outnumbered sellers: 124 funds opened new EXEL positions and 42 closed out — a net gain of 82 holders — while 235 added to existing stakes and 214 trimmed.

The largest buyer was Qube Research & Technologies (QRT), adding an estimated $66.6M. The largest seller was Farallon Capital Management, cutting an estimated $260M.

  • 633 institutional investors held Exelixis (EXEL) as of Q2 2025, up from 557 in Q1 2025.
  • Funds reported $11.2B of Exelixis stock for Q2 2025, up 20% quarter-over-quarter.
  • 124 funds opened new Exelixis positions in Q2 2025 and 42 closed out, a net change of +82 holders.
  • The largest Exelixis buyer in Q2 2025 was Qube Research & Technologies (QRT), an estimated $66.6M added.
  • The largest Exelixis seller in Q2 2025 was Farallon Capital Management, an estimated $260M sold.

Based on aggregated 13F filings for Q2 2025.