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Exelixis

633 hedge funds and large institutions have $11.2B invested in Exelixis in 2025 Q2 according to their latest regulatory filings, with 124 funds opening new positions, 235 increasing their positions, 214 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

195% more first-time investments, than exits

New positions opened: 124 | Existing positions closed: 42

20% more capital invested

Capital invested by funds: $9.38B → $11.2B (+$1.85B)

14% more funds holding

Funds holding: 557633 (+76)

2.64% more ownership

Funds ownership: 90.86%93.5% (+2.6%)

10% more repeat investments, than reductions

Existing positions increased: 235 | Existing positions reduced: 214

7% more call options, than puts

Call options by funds: $82.8M | Put options by funds: $77.6M

0% more funds holding in top 10

Funds holding in top 10: 1010 (0)

Holders
633
Holders Change
+76
Holders Change %
+13.64%
% of All Funds
8.33%
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.13%
New
124
Increased
235
Reduced
214
Closed
42
Calls
$82.8M
Puts
$77.6M
Net Calls
+$5.2M
Net Calls Change
-$38M
Name Holding Trade Value Shares
Change
Change in
Stake
BFM
51
Boothbay Fund Management
New York
$35.5M +$16.3K +407 +0.1%
Federated Hermes
52
Federated Hermes
Pennsylvania
$35.3M +$12.7M +317,866 +66%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$34.2M -$1.13M -28,210 -4%
WP
54
Woodline Partners
California
$31.9M -$3.67M -91,877 -11%
Ameriprise
55
Ameriprise
Minnesota
$31.8M +$10.4M +259,189 +56%
Citigroup
56
Citigroup
New York
$30.7M +$9.27M +231,800 +50%
Barclays
57
Barclays
United Kingdom
$29.1M +$10.7M +267,007 +68%
Two Sigma Investments
58
Two Sigma Investments
New York
$28.3M -$38.3M -957,984 -60%
TI
59
Trexquant Investment
Connecticut
$27.7M +$20.3M +507,919 +418%
Assenagon Asset Management
60
Assenagon Asset Management
Luxembourg
$27.5M -$4.34M -108,572 -15%
Principal Financial Group
61
Principal Financial Group
Iowa
$27.3M -$1.13M -28,215 -4%
D.E. Shaw & Co
62
D.E. Shaw & Co
New York
$26.6M -$4.37M -109,219 -15%
BNP Paribas Financial Markets
63
BNP Paribas Financial Markets
France
$26.5M +$7.05M +176,373 +42%
EAM
64
EULAV Asset Management
Florida
$26.2M +$2.6M +65,067 +12%
CS
65
Candriam SCA
Luxembourg
$25.9M +$9.3M +232,597 +65%
DB
66
Danske Bank
Denmark
$25.7M +$3.23M +80,793 +16%
Millennium Management
67
Millennium Management
New York
$25.7M +$4.33M +108,326 +23%
Legal & General Group
68
Legal & General Group
United Kingdom
$25.6M -$22.9K -572 -0.1%
Canada Pension Plan Investment Board
69
Canada Pension Plan Investment Board
Ontario, Canada
$24M -$3.87M -96,800 -15%
California Public Employees Retirement System
70
California Public Employees Retirement System
California
$23.2M -$30.5M -762,866 -59%
Janus Henderson Group
71
Janus Henderson Group
United Kingdom
$22M +$12.6M +314,279 +170%
KAM
72
Krensavage Asset Management
New York
$21.8M -$15.4M -385,007 -44%
Russell Investments Group
73
Russell Investments Group
United Kingdom
$21.6M -$4.73M -118,223 -19%
Swiss National Bank
74
Swiss National Bank
Switzerland
$21.2M -$664K -16,600 -3%
Universal-Beteiligungs- und Servicegesellschaft
75
Universal-Beteiligungs- und Servicegesellschaft
Germany
$20.2M +$1.53M +38,347 +9%

EXEL Hedge Fund Activity: Q2 2025 in Review

633 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Exelixis (EXEL) for Q2 2025, worth a combined $11.2B — up 20% from $9.38B a quarter earlier.

Buyers outnumbered sellers: 124 funds opened new EXEL positions and 42 closed out — a net gain of 82 holders — while 235 added to existing stakes and 214 trimmed.

The largest buyer was Qube Research & Technologies (QRT), adding an estimated $66.6M. The largest seller was Farallon Capital Management, cutting an estimated $260M.

  • 633 institutional investors held Exelixis (EXEL) as of Q2 2025, up from 557 in Q1 2025.
  • Funds reported $11.2B of Exelixis stock for Q2 2025, up 20% quarter-over-quarter.
  • 124 funds opened new Exelixis positions in Q2 2025 and 42 closed out, a net change of +82 holders.
  • The largest Exelixis buyer in Q2 2025 was Qube Research & Technologies (QRT), an estimated $66.6M added.
  • The largest Exelixis seller in Q2 2025 was Farallon Capital Management, an estimated $260M sold.

Based on aggregated 13F filings for Q2 2025.