|
1
|
Flagship Pioneering
Cambridge,
Massachusetts
|
$111M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$20.2M
|
-$397K
|
-2,885
|
-2%
|
|
|
3
|
Harbourvest Partners
Boston,
Massachusetts
|
$10.8M
|
–
|
–
|
–
|
|
|
4
|
Credit Suisse
Zurich,
Switzerland
|
$7.1M
|
+$419K
|
+3,051
|
+6%
|
|
|
5
|
Alphabet Inc
Mountain View,
California
|
$6.47M
|
–
|
–
|
–
|
|
|
6
|
|
$4.59M
|
+$670K
|
+4,871
|
+15%
|
|
|
7
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$4.47M
|
+$434K
|
+3,160
|
+9%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.61M
|
-$51K
|
-371
|
-2%
|
|
|
9
|
Samsara BioCapital
Palo Alto,
California
|
$1.39M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$1.35M
|
+$1.79K
|
+13
|
+0.1%
|
|
|
11
|
Northern Trust
Chicago,
Illinois
|
$847K
|
-$1.38K
|
-10
|
-0.1%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$726K
|
+$2.06K
|
+15
|
+0.3%
|
|
|
13
|
Victory Capital Management
San Antonio,
Texas
|
$583K
|
+$217K
|
+1,576
|
+49%
|
|
|
14
|
Charles Schwab
San Francisco,
California
|
$465K
|
+$220K
|
+1,598
|
+72%
|
|
|
15
|
|
$451K
|
+$66.4K
|
+483
|
+15%
|
|
|
16
|
HSBC Holdings
London,
United Kingdom
|
$314K
|
+$354K
|
+2,575
|
New
|
|
|
17
|
Bank of New York Mellon
New York
|
$252K
|
-$15.5K
|
-113
|
-5%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$210K
|
-$17.2K
|
-125
|
-7%
|
|
|
19
|
Wells Fargo
San Francisco,
California
|
$173K
|
+$26K
|
+189
|
+15%
|
|
|
20
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$132K
|
–
|
–
|
–
|
|
|
21
|
RhumbLine Advisers
Boston,
Massachusetts
|
$122K
|
+$9.76K
|
+71
|
+8%
|
|
|
22
|
DAFNA Capital Management
Los Angeles,
California
|
$122K
|
+$137K
|
+1,000
|
New
|
|
|
23
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
$118K
|
–
|
–
|
–
|
|
|
24
|
Renaissance Technologies
New York
|
$88K
|
+$99.7K
|
+725
|
New
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$80K
|
+$64.6K
|
+470
|
+257%
|
|
