|
1
|
RA Capital Management
Boston,
Massachusetts
|
$128M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$99.6M
|
+$44.9M
|
+4,885,938
|
+121%
|
|
|
3
|
|
$62.3M
|
+$51.3M
|
+5,578,931
|
New
|
|
|
4
|
|
$60.9M
|
+$4.49M
|
+487,956
|
+10%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$60.3M
|
+$10M
|
+1,092,718
|
+25%
|
|
|
6
|
Suvretta Capital Management
New York
|
$54.6M
|
+$20.2M
|
+2,194,030
|
+81%
|
|
|
7
|
Pictet Asset Management
Carouge,
Switzerland
|
$50.9M
|
+$6.16M
|
+669,726
|
+17%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$48.1M
|
+$7.19M
|
+781,803
|
+22%
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$45.2M
|
+$20.2M
|
+2,201,200
|
+119%
|
|
|
10
|
Holocene Advisors
New York
|
$39M
|
+$11.5M
|
+1,254,823
|
+56%
|
|
|
11
|
Adage Capital Partners
Boston,
Massachusetts
|
$34.9M
|
+$13.1M
|
+1,426,583
|
+84%
|
|
|
12
|
Laurion Capital Management
New York
|
$30.2M
|
+$13.8M
|
+1,498,564
|
+124%
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$24.3M
|
+$6.2M
|
+674,330
|
+45%
|
|
|
14
|
Frazier Life Sciences Management
Palo Alto,
California
|
$22.3M
|
+$18.4M
|
+2,000,000
|
New
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$22M
|
+$11.1M
|
+1,207,447
|
+158%
|
|
|
16
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$21.9M
|
-$1.54M
|
-167,035
|
-8%
|
|
|
17
|
Westfield Capital Management
Boston,
Massachusetts
|
$19.7M
|
+$4.13M
|
+449,262
|
+34%
|
|
|
18
|
|
$16.6M
|
+$8.18M
|
+889,506
|
+148%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$15.4M
|
+$770K
|
+83,722
|
+6%
|
|
|
20
|
Superstring Capital Management
New York
|
$11.4M
|
+$9.39M
|
+1,021,477
|
New
|
|
|
21
|
Franklin Resources
San Mateo,
California
|
$9.25M
|
+$2.94K
|
+320
|
+0%
|
|
|
22
|
Orchard Capital Management
Chicago,
Illinois
|
$8.26M
|
+$1.8M
|
+196,329
|
+36%
|
|
|
23
|
Eagle Asset Management
St Petersburg,
Florida
|
$7.84M
|
-$99.3K
|
-10,803
|
-2%
|
|
|
24
|
|
$7.05M
|
+$1.03M
|
+112,438
|
+22%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$6.9M
|
+$343K
|
+37,339
|
+6%
|
|
