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Esperion Therapeutics

200 hedge funds and large institutions have $560M invested in Esperion Therapeutics in 2025 Q4 according to their latest regulatory filings, with 43 funds opening new positions, 83 increasing their positions, 34 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

350% more call options, than puts

Call options by funds: $19.2M | Put options by funds: $4.26M

144% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 34

96% more capital invested

Capital invested by funds: $286M → $560M (+$274M)

54% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 28

9.73% more ownership

Funds ownership: 53.55%63.28% (+9.7%)

6% more funds holding

Funds holding: 188200 (+12)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
200
Holders Change
+12
Holders Change %
+6.38%
% of All Funds
2.43%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
43
Increased
83
Reduced
34
Closed
28
Calls
$19.2M
Puts
$4.26M
Net Calls
+$14.9M
Net Calls Change
+$14.6M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$65.4M +$9.2M +2,848,410 +19%
Vanguard Group
2
Vanguard Group
Pennsylvania
$55.3M +$9.22M +2,853,005 +24%
TSC
3
Two Seas Capital
New York
$44M +$6.96M +2,152,797 +22%
WA
4
Wasatch Advisors
Utah
$34.9M +$7.7M +2,383,902 +34%
D.E. Shaw & Co
5
D.E. Shaw & Co
New York
$25.5M +$21.6M +6,694,850 +3,209%
O
6
OrbiMed
New York
$22.1M +$19.3M +5,965,498 New
State Street
7
State Street
Massachusetts
$21.9M +$4.69M +1,451,462 +32%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$21.2M +$3.19M +986,255 +21%
Marshall Wace
9
Marshall Wace
United Kingdom
$20.2M +$9.53M +2,950,172 +117%
Two Sigma Investments
10
Two Sigma Investments
New York
$17.5M +$8.09M +2,503,464 +112%
PCM
11
PenderFund Capital Management
British Columbia, Canada
$16.3M -$7.38M -2,284,593 -34%
ACM
12
AIGH Capital Management
Maryland
$14.8M +$3.23M +1,000,000 +33%
Millennium Management
13
Millennium Management
New York
$14.5M +$9.56M +2,957,418 +303%
EP
14
Eversept Partners
New York
$14.2M +$12.4M +3,851,133 New
N
15
Nuveen
North Carolina
$13.4M -$320K -98,956 -3%
RA
16
Royce & Associates
New York
$13.3M +$4.23M +1,308,035 +57%
Morgan Stanley
17
Morgan Stanley
New York
$13M -$1.75M -541,399 -13%
Two Sigma Advisers
18
Two Sigma Advisers
New York
$13M +$5.16M +1,597,200 +84%
Goldman Sachs
19
Goldman Sachs
New York
$10.5M +$3.68M +1,139,409 +67%
Renaissance Technologies
20
Renaissance Technologies
New York
$8.12M +$4.59M +1,420,700 +184%
Jones Financial Companies
21
Jones Financial Companies
Missouri
$7.75M +$6.76M +2,093,164 +167,721%
Northern Trust
22
Northern Trust
Illinois
$7.38M +$476K +147,269 +8%
Walleye Capital
23
Walleye Capital
New York
$5.81M +$4.04M +1,250,025 +392%
VCIM
24
Velan Capital Investment Management
Georgia
$4.48M +$3.91M +1,210,000 New
VCM
25
Voleon Capital Management
California
$4.27M +$3.06M +946,510 +455%