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154 hedge funds and large institutions have $816M invested in Erasca in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,833% more call options, than puts

Call options by funds: $10.9M | Put options by funds: $221K

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

74% more capital invested

Capital invested by funds: $469M → $816M (+$347M)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more funds holding

Funds holding: 141154 (+13)

1.53% more ownership

Funds ownership: 75.76%77.29% (+1.5%)

6% less repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 47

Holders
154
Holders Change
+13
Holders Change %
+9.22%
% of All Funds
1.87%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
32
Increased
44
Reduced
47
Closed
18
Calls
$10.9M
Puts
$221K
Net Calls
+$10.7M
Net Calls Change
+$10.1M
Name Holding Trade Value Shares
Change
Change in
Stake
IA
151
IFP Advisors
Florida
$350
AAP
152
Arax Advisory Partners
Colorado
$89 -$21.5K -7,657 -100%
PNC Financial Services Group
153
PNC Financial Services Group
Pennsylvania
$30
SCM
154
Sio Capital Management
New York
-$2.99M -1,369,748 Closed
IIA
155
IPG Investment Advisors
California
-$497K -227,994 Closed
AA
156
ALPS Advisors
Colorado
-$289K -132,499 Closed
Walleye Capital
157
Walleye Capital
New York
-$220K -100,931 Closed
VCIM
158
Velan Capital Investment Management
Georgia
-$142K -65,000 Closed
GCM
159
Graham Capital Management
Connecticut
-$137K -62,705 Closed
GCP
160
GSA Capital Partners
United Kingdom
-$137K -62,678 Closed
Los Angeles Capital Management
161
Los Angeles Capital Management
California
-$76.5K -35,075 Closed
EGM
162
Engineers Gate Manager
New York
-$75.3K -34,523 Closed
QI
163
Qtron Investments
Massachusetts
-$73.2K -33,593 Closed
CWM
164
Crowley Wealth Management
Delaware
-$32.7K -15,000 Closed
Principal Financial Group
165
Principal Financial Group
Iowa
-$29.2K -13,380 Closed
GS
166
GTS Securities
New York
-$23.5K -10,775 Closed
Group One Trading
167
Group One Trading
Illinois
-$8.59K -3,054 Closed
US Bancorp
168
US Bancorp
Minnesota
-$3.46K -1,587 Closed
RA
169
Rise Advisors
New York
-$796 -365 Closed
CA
170
Clearstead Advisors
Ohio
-$5 -2 Closed

ERAS Hedge Fund Activity: Q4 2025 in Review

154 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q4 2025, worth a combined $816M — up 74% from $469M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new ERAS positions and 18 closed out — a net gain of 14 holders — while 44 added to existing stakes and 47 trimmed.

The largest buyer was State Street, adding an estimated $6.03M. The largest seller was T. Rowe Price Investment Management, cutting an estimated $11.6M.

  • 154 institutional investors held Erasca (ERAS) as of Q4 2025, up from 141 in Q3 2025.
  • Funds reported $816M of Erasca stock for Q4 2025, up 74% quarter-over-quarter.
  • 32 funds opened new Erasca positions in Q4 2025 and 18 closed out, a net change of +14 holders.
  • The largest Erasca buyer in Q4 2025 was State Street, an estimated $6.03M added.
  • The largest Erasca seller in Q4 2025 was T. Rowe Price Investment Management, an estimated $11.6M sold.

Based on aggregated 13F filings for Q4 2025.