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154 hedge funds and large institutions have $816M invested in Erasca in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,833% more call options, than puts

Call options by funds: $10.9M | Put options by funds: $221K

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

74% more capital invested

Capital invested by funds: $469M → $816M (+$347M)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more funds holding

Funds holding: 141154 (+13)

1.53% more ownership

Funds ownership: 75.76%77.29% (+1.5%)

6% less repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 47

Holders
154
Holders Change
+13
Holders Change %
+9.22%
% of All Funds
1.87%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
32
Increased
44
Reduced
47
Closed
18
Calls
$10.9M
Puts
$221K
Net Calls
+$10.7M
Net Calls Change
+$10.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Legal & General Group
101
Legal & General Group
United Kingdom
$57.5K
SPA
102
Sherbrooke Park Advisers
New York
$56.9K +$43K +15,300 New
WAP
103
Wealthcare Advisory Partners
Pennsylvania
$56.4K +$42.7K +15,168 New
AIP
104
Ameritas Investment Partners
Nebraska
$54.5K -$9.38K -3,335 -19%
Russell Investments Group
105
Russell Investments Group
United Kingdom
$53.5K
BP
106
Ballentine Partners
Massachusetts
$52.1K
PCA
107
Pallas Capital Advisors
Massachusetts
$51.8K +$115 +41 +0.3%
Mirae Asset Global Investments
108
Mirae Asset Global Investments
South Korea
$51.3K +$7.93K +2,820 +26%
X
109
Xponance
Pennsylvania
$50.2K
QC
110
Quadrature Capital
United Kingdom
$49K +$37K +13,162 New
Prudential Financial
111
Prudential Financial
New Jersey
$47.4K -$15.2K -5,406 -30%
Neuberger Berman Group
112
Neuberger Berman Group
New York
$46K +$3.52K +1,253 +11%
CWM
113
CIBC World Markets
New York
$42.7K +$32.3K +11,484 New
Two Sigma Advisers
114
Two Sigma Advisers
New York
$42K -$172K -61,100 -84%
Mariner
115
Mariner
Kansas
$40.3K +$30.4K +10,825 New
XT
116
XTX Topco
Cayman Islands
$40.2K +$30.4K +10,798 New
California State Teachers Retirement System (CalSTRS)
117
California State Teachers Retirement System (CalSTRS)
California
$39.8K -$498 -177 -2%
Mackenzie Financial
118
Mackenzie Financial
Ontario, Canada
$39.4K
Stifel Financial
119
Stifel Financial
Missouri
$38.3K +$29K +10,300 New
EC
120
EntryPoint Capital
New York
$38.3K +$28.9K +10,293 New
SCM
121
Sterling Capital Management
North Carolina
$37.6K -$5.27K -1,874 -16%
AC
122
AlphaCore Capital
California
$37.2K
Canada Pension Plan Investment Board
123
Canada Pension Plan Investment Board
Ontario, Canada
$29.8K +$22.5K +8,000 New
S
124
SignatureFD
Georgia
$26.4K
TRCT
125
Tower Research Capital (TRC)
New York
$25.6K -$12K -4,263 -38%

ERAS Hedge Fund Activity: Q4 2025 in Review

154 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q4 2025, worth a combined $816M — up 74% from $469M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new ERAS positions and 18 closed out — a net gain of 14 holders — while 44 added to existing stakes and 47 trimmed.

The largest buyer was State Street, adding an estimated $6.03M. The largest seller was T. Rowe Price Investment Management, cutting an estimated $11.6M.

  • 154 institutional investors held Erasca (ERAS) as of Q4 2025, up from 141 in Q3 2025.
  • Funds reported $816M of Erasca stock for Q4 2025, up 74% quarter-over-quarter.
  • 32 funds opened new Erasca positions in Q4 2025 and 18 closed out, a net change of +14 holders.
  • The largest Erasca buyer in Q4 2025 was State Street, an estimated $6.03M added.
  • The largest Erasca seller in Q4 2025 was T. Rowe Price Investment Management, an estimated $11.6M sold.

Based on aggregated 13F filings for Q4 2025.