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154 hedge funds and large institutions have $816M invested in Erasca in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,833% more call options, than puts

Call options by funds: $10.9M | Put options by funds: $221K

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

74% more capital invested

Capital invested by funds: $469M → $816M (+$347M)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more funds holding

Funds holding: 141154 (+13)

1.53% more ownership

Funds ownership: 75.76%77.29% (+1.5%)

6% less repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 47

Holders
154
Holders Change
+13
Holders Change %
+9.22%
% of All Funds
1.87%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
32
Increased
44
Reduced
47
Closed
18
Calls
$10.9M
Puts
$221K
Net Calls
+$10.7M
Net Calls Change
+$10.1M
Name Holding Trade Value Shares
Change
Change in
Stake
New York State Common Retirement Fund
76
New York State Common Retirement Fund
New York
$207K -$13.8K -4,893 -8%
Manulife (Manufacturers Life Insurance)
77
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$204K -$19.8K -7,032 -11%
Tudor Investment Corp
78
Tudor Investment Corp
Connecticut
$199K +$150K +53,436 New
BHCM
79
Brevan Howard Capital Management
Jersey
$196K -$107K -38,015 -42%
PA
80
Profund Advisors
Maryland
$188K +$142K +50,605 New
SG Americas Securities
81
SG Americas Securities
New York
$181K +$95.8K +34,072 +233%
CUAMC
82
China Universal Asset Management Company
China
$172K -$9.82K -3,492 -7%
ProShare Advisors
83
ProShare Advisors
Maryland
$164K +$12.5K +4,430 +11%
PFSRSONJ
84
Police & Firemen's Retirement System of New Jersey
New Jersey
$164K -$42.5K -15,123 -26%
JG
85
Jain Global
New York
$157K +$119K +42,336 New
Two Sigma Investments
86
Two Sigma Investments
New York
$141K -$871K -309,743 -89%
B
87
Bailard
California
$131K +$99.1K +35,238 New
VPIM
88
Vanguard Personalized Indexing Management
California
$129K -$402 -143 -0.4%
Carson Wealth (CWM LLC)
89
Carson Wealth (CWM LLC)
Nebraska
$125K +$858 +305 +0.9%
VOYA Investment Management
90
VOYA Investment Management
Georgia
$123K
BNP Paribas Financial Markets
91
BNP Paribas Financial Markets
France
$121K -$16K -5,675 -15%
EWA
92
EP Wealth Advisors
California
$112K +$84.4K +30,000 New
YIH
93
Y-Intercept (HK)
Hong Kong
$90.4K +$68.4K +24,311 New
Wealth Enhancement Advisory Services
94
Wealth Enhancement Advisory Services
Minnesota
$81.7K +$1.02K +362 +2%
AC
95
AXQ Capital
New Jersey
$76.1K +$57.5K +20,459 New
Victory Capital Management
96
Victory Capital Management
Texas
$68.4K -$397 -141 -0.8%
CAPTRUST Financial Advisors
97
CAPTRUST Financial Advisors
North Carolina
$65.5K -$14.9K -5,295 -23%
QCG
98
Quadrant Capital Group
Ohio
$65.3K
SEI Investments
99
SEI Investments
Pennsylvania
$62.1K
AHL
100
Abel Hall LLC
Louisiana
$58.3K +$44.1K +15,682 New

ERAS Hedge Fund Activity: Q4 2025 in Review

154 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q4 2025, worth a combined $816M — up 74% from $469M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new ERAS positions and 18 closed out — a net gain of 14 holders — while 44 added to existing stakes and 47 trimmed.

The largest buyer was State Street, adding an estimated $6.03M. The largest seller was T. Rowe Price Investment Management, cutting an estimated $11.6M.

  • 154 institutional investors held Erasca (ERAS) as of Q4 2025, up from 141 in Q3 2025.
  • Funds reported $816M of Erasca stock for Q4 2025, up 74% quarter-over-quarter.
  • 32 funds opened new Erasca positions in Q4 2025 and 18 closed out, a net change of +14 holders.
  • The largest Erasca buyer in Q4 2025 was State Street, an estimated $6.03M added.
  • The largest Erasca seller in Q4 2025 was T. Rowe Price Investment Management, an estimated $11.6M sold.

Based on aggregated 13F filings for Q4 2025.