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154 hedge funds and large institutions have $816M invested in Erasca in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,833% more call options, than puts

Call options by funds: $10.9M | Put options by funds: $221K

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

74% more capital invested

Capital invested by funds: $469M → $816M (+$347M)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more funds holding

Funds holding: 141154 (+13)

1.53% more ownership

Funds ownership: 75.76%77.29% (+1.5%)

6% less repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 47

Holders
154
Holders Change
+13
Holders Change %
+9.22%
% of All Funds
1.87%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
32
Increased
44
Reduced
47
Closed
18
Calls
$10.9M
Puts
$221K
Net Calls
+$10.7M
Net Calls Change
+$10.1M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
51
D.E. Shaw & Co
New York
$751K +$568K +201,938 New
Susquehanna International Group
52
Susquehanna International Group
Pennsylvania
$743K +$260K +92,546 +86%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$703K -$35.3K -12,538 -6%
BFM
54
Boothbay Fund Management
New York
$701K +$530K +188,467 New
UBS Group
55
UBS Group
Switzerland
$634K +$68.5K +24,370 +17%
American Century Companies
56
American Century Companies
Missouri
$615K +$365K +129,905 +366%
Hudson Bay Capital Management
57
Hudson Bay Capital Management
Connecticut
$588K +$444K +158,020 New
RI
58
RTW Investments
New York
$546K +$412K +146,651 New
PWM
59
Palumbo Wealth Management
New York
$519K +$41.8K +14,852 +12%
Rafferty Asset Management
60
Rafferty Asset Management
New York
$487K +$368K +131,019 New
Deutsche Bank
61
Deutsche Bank
Germany
$454K -$124K -43,918 -26%
PAM
62
Panagora Asset Management
Massachusetts
$440K +$44.5K +15,839 +15%
T. Rowe Price Associates
63
T. Rowe Price Associates
Maryland
$386K +$27.9K +9,923 +11%
Balyasny Asset Management
64
Balyasny Asset Management
Illinois
$365K -$6.71K -2,386 -2%
Citigroup
65
Citigroup
New York
$356K +$226K +80,524 +528%
IIM
66
INTECH Investment Management
Florida
$337K +$30.2K +10,745 +13%
Mirae Asset Global ETFs Holdings
67
Mirae Asset Global ETFs Holdings
Hong Kong
$327K +$18.8K +6,698 +8%
MIM
68
MetLife Investment Management
New Jersey
$299K -$27.2K -9,682 -11%
CAM
69
Cresset Asset Management
Illinois
$297K
VIA
70
Virtus Investment Advisers
Connecticut
$275K -$1.34K -475 -0.6%
SRL
71
Scientech Research LLC
New Jersey
$269K +$203K +72,203 New
Marshall Wace
72
Marshall Wace
United Kingdom
$230K -$1.3M -464,049 -88%
Cerity Partners
73
Cerity Partners
New York
$229K +$340 +121 +0.2%
IC
74
IEQ Capital
California
$224K -$8.06K -2,868 -5%
SPS
75
Susquehanna Portfolio Strategies
Pennsylvania
$220K +$61.3K +21,787 +58%

ERAS Hedge Fund Activity: Q4 2025 in Review

154 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q4 2025, worth a combined $816M — up 74% from $469M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new ERAS positions and 18 closed out — a net gain of 14 holders — while 44 added to existing stakes and 47 trimmed.

The largest buyer was State Street, adding an estimated $6.03M. The largest seller was T. Rowe Price Investment Management, cutting an estimated $11.6M.

  • 154 institutional investors held Erasca (ERAS) as of Q4 2025, up from 141 in Q3 2025.
  • Funds reported $816M of Erasca stock for Q4 2025, up 74% quarter-over-quarter.
  • 32 funds opened new Erasca positions in Q4 2025 and 18 closed out, a net change of +14 holders.
  • The largest Erasca buyer in Q4 2025 was State Street, an estimated $6.03M added.
  • The largest Erasca seller in Q4 2025 was T. Rowe Price Investment Management, an estimated $11.6M sold.

Based on aggregated 13F filings for Q4 2025.