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141 hedge funds and large institutions have $469M invested in Erasca in 2025 Q3 according to their latest regulatory filings, with 17 funds opening new positions, 41 increasing their positions, 43 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

735% more call options, than puts

Call options by funds: $618K | Put options by funds: $74K

69% more capital invested

Capital invested by funds: $277M → $469M (+$191M)

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

6% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 16

1% less funds holding

Funds holding: 142141 (-1)

5% less repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 43

1.23% less ownership

Funds ownership: 76.99%75.76% (-1.2%)

Holders
141
Holders Change
-1
Holders Change %
-0.7%
% of All Funds
1.85%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
17
Increased
41
Reduced
43
Closed
16
Calls
$618K
Puts
$74K
Net Calls
+$544K
Net Calls Change
+$215K
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
26
Sio Capital Management
New York
$2.99M
SCM
27
Silverarc Capital Management
Massachusetts
$2.98M -$1.91M -1,201,516 -47%
JP Morgan Chase
28
JP Morgan Chase
New York
$2.77M -$165K -103,527 -8%
Renaissance Technologies
29
Renaissance Technologies
New York
$2.21M +$433K +272,505 +37%
Royal Bank of Canada
30
Royal Bank of Canada
Ontario, Canada
$1.46M +$101K +63,366 +10%
AQR Capital Management
31
AQR Capital Management
Connecticut
$1.45M -$69.5K -43,721 -6%
Wellington Management Group
32
Wellington Management Group
Massachusetts
$1.31M -$453K -285,071 -32%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$1.25M +$29.8K +18,741 +3%
Marshall Wace
34
Marshall Wace
United Kingdom
$1.15M -$2.46M -1,548,416 -75%
N
35
Nuveen
North Carolina
$981K
Fidelity Investments
36
Fidelity Investments
Massachusetts
$915K +$67.7K +42,578 +11%
Jane Street
37
Jane Street
New York
$842K +$404K +253,800 +192%
Creative Planning
38
Creative Planning
Kansas
$764K +$169K +105,982 +43%
DCM
39
DAFNA Capital Management
California
$763K
Two Sigma Investments
40
Two Sigma Investments
New York
$758K -$127K -79,836 -19%
Citadel Advisors
41
Citadel Advisors
Florida
$745K +$544K +341,799 New
Invesco
42
Invesco
Georgia
$615K +$175K +109,799 +64%
Morgan Stanley
43
Morgan Stanley
New York
$586K -$542K -340,673 -56%
Barclays
44
Barclays
United Kingdom
$585K -$87.8K -55,228 -17%
TD Asset Management
45
TD Asset Management
Ontario, Canada
$558K
AllianceBernstein
46
AllianceBernstein
Tennessee
$509K
IIA
47
IPG Investment Advisors
California
$497K -$32K -20,114 -8%
RhumbLine Advisers
48
RhumbLine Advisers
Massachusetts
$439K +$54 +34 +0%
Deutsche Bank
49
Deutsche Bank
Germany
$362K +$264K +165,895 New
Wells Fargo
50
Wells Fargo
California
$346K +$34.5K +21,705 +16%

ERAS Hedge Fund Activity: Q3 2025 in Review

141 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q3 2025, worth a combined $469M — up 69% from $277M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new ERAS positions and 16 closed out — a net gain of 1 holder — while 41 added to existing stakes and 43 trimmed.

The largest buyer was Vivo Capital, adding an estimated $4M. The largest seller was Marshall Wace, cutting an estimated $2.46M.

  • 141 institutional investors held Erasca (ERAS) as of Q3 2025, down from 142 in Q2 2025.
  • Funds reported $469M of Erasca stock for Q3 2025, up 69% quarter-over-quarter.
  • 17 funds opened new Erasca positions in Q3 2025 and 16 closed out, a net change of +1 holder.
  • The largest Erasca buyer in Q3 2025 was Vivo Capital, an estimated $4M added.
  • The largest Erasca seller in Q3 2025 was Marshall Wace, an estimated $2.46M sold.

Based on aggregated 13F filings for Q3 2025.