ESSA Pharma
EPIX
EPIX was delisted on the 8th of October, 2025.
60 hedge funds and large institutions have $530M invested in ESSA Pharma in 2021 Q4 according to their latest regulatory filings, with 6 funds opening new positions, 25 increasing their positions, 19 reducing their positions, and 21 closing their positions.
1,800% more call options, than puts
Call options by funds: $171K | Put options by funds: $9K
78% more capital invested
Capital invested by funds: $297M → $530M (+$233M)
32% more repeat investments, than reductions
Existing positions increased: 25 | Existing positions reduced: 19
0.37% more ownership
Funds ownership: 84.52% → 84.89% (+0.37%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
20% less funds holding
Funds holding: 75 → 60 (-15)
71% less first-time investments, than exits
New positions opened: 6 | Existing positions closed: 21
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
EAM
Eventide Asset Management
Boston,
Massachusetts
|
+$12.7M |
| 2 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
+$7.32M |
| 3 |
WP
Woodline Partners
San Francisco,
California
|
+$5.65M |
| 4 |
ACM
Altium Capital Management
New York
|
+$3.84M |
| 5 |
CS
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
+$3.63M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Two Sigma Investments
New York
|
-$5.4M |
| 2 |
Two Sigma Advisers
New York
|
-$4.55M |
| 3 |
VC
Vivo Capital
Palo Alto,
California
|
-$3.48M |
| 4 |
Citadel Advisors
Miami,
Florida
|
-$2.25M |
| 5 |
D.E. Shaw & Co
New York
|
-$2.02M |
EPIX Hedge Fund Activity: Q4 2021 in Review
60 of the 6,518 institutional investors tracked by Wall St. Rank reported a position in ESSA Pharma (EPIX) for Q4 2021, worth a combined $530M — up 78% from $297M a quarter earlier.
Sellers outnumbered buyers: 21 funds closed out of EPIX and 6 opened new positions — a net loss of 15 holders — while 19 trimmed existing stakes and 25 added.
The largest buyer was Eventide Asset Management, adding an estimated $12.7M. The largest seller was Two Sigma Investments, cutting an estimated $5.4M.
- 60 institutional investors held ESSA Pharma (EPIX) as of Q4 2021, down from 75 in Q3 2021.
- Funds reported $530M of ESSA Pharma stock for Q4 2021, up 78% quarter-over-quarter.
- 6 funds opened new ESSA Pharma positions in Q4 2021 and 21 closed out, a net change of -15 holders.
- The largest ESSA Pharma buyer in Q4 2021 was Eventide Asset Management, an estimated $12.7M added.
- The largest ESSA Pharma seller in Q4 2021 was Two Sigma Investments, an estimated $5.4M sold.
Based on aggregated 13F filings for Q4 2021.