|
1
|
|
$160M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$152M
|
+$18M
|
+950,372
|
+14%
|
|
|
3
|
Commodore Capital
New York
|
$94.1M
|
+$337K
|
+17,809
|
+0.4%
|
|
|
4
|
|
$80.8M
|
–
|
–
|
–
|
|
|
5
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$74.5M
|
+$9.63M
|
+508,646
|
+16%
|
|
|
6
|
Polar Capital Holdings
London,
United Kingdom
|
$61.2M
|
+$13M
|
+685,000
|
+29%
|
|
|
7
|
|
$59.5M
|
-$587K
|
-30,995
|
-1%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$48.4M
|
+$8.3M
|
+438,397
|
+22%
|
|
|
9
|
Janus Henderson Group
London,
|
$34.4M
|
+$2.76M
|
+145,909
|
+9%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$29.5M
|
+$6.57M
|
+347,286
|
+31%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$27.1M
|
+$23M
|
+1,213,160
|
+867%
|
|
|
12
|
|
$26.5M
|
+$10.6M
|
+558,285
|
+73%
|
|
|
13
|
Capital Research Global Investors
Los Angeles,
California
|
$26.4M
|
+$24.9M
|
+1,315,465
|
New
|
|
|
14
|
Woodline Partners
San Francisco,
California
|
$22.1M
|
+$5.59M
|
+295,500
|
+37%
|
|
|
15
|
Novo Holdings A/S
Hellerup,
Denmark
|
$21.8M
|
+$20.5M
|
+1,084,432
|
New
|
|
|
16
|
Pictet Asset Management
Carouge,
Switzerland
|
$19.4M
|
–
|
–
|
–
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$17.7M
|
+$1.2M
|
+63,580
|
+8%
|
|
|
18
|
RA Capital Management
Boston,
Massachusetts
|
$17M
|
–
|
–
|
–
|
|
|
19
|
State Street
Boston,
Massachusetts
|
$16.4M
|
+$669K
|
+35,340
|
+5%
|
|
|
20
|
5AM Venture Management
San Francisco,
California
|
$15.5M
|
-$10.4M
|
-550,000
|
-42%
|
|
|
21
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$14.1M
|
+$4.46M
|
+235,537
|
+51%
|
|
|
22
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$10.6M
|
+$9.69M
|
+512,090
|
+3,169%
|
|
|
23
|
First Turn Management
Del Mar,
California
|
$10.2M
|
-$475K
|
-25,105
|
-5%
|
|
|
24
|
TCG Crossover Management
Palo Alto,
California
|
$9.99M
|
+$9.43M
|
+498,000
|
New
|
|
|
25
|
Duquesne Family Office
New York
|
$9.29M
|
+$8.77M
|
+463,000
|
New
|
|
