|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$187M
|
+$142M
|
+5,402,030
|
New
|
|
|
2
|
Polaris Venture Management Co VI
Boston,
Massachusetts
|
$161M
|
+$122M
|
+4,656,173
|
New
|
|
|
3
|
Viking Global Investors
Stamford,
Connecticut
|
$73.8M
|
+$56.1M
|
+2,135,523
|
New
|
|
|
4
|
Deerfield Management
New York
|
$59M
|
+$44.9M
|
+1,709,400
|
New
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$47.2M
|
+$37.1M
|
+1,409,896
|
New
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$25.9M
|
+$19.7M
|
+750,292
|
New
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$10.2M
|
+$7.75M
|
+295,000
|
New
|
|
|
8
|
Alphabet Inc
Mountain View,
California
|
$8.86M
|
+$6.74M
|
+256,410
|
New
|
|
|
9
|
Wildcat Capital Management
New York
|
$8.56M
|
+$6.51M
|
+247,768
|
New
|
|
|
10
|
Jennison Associates
New York
|
$5.7M
|
+$4.49M
|
+170,940
|
New
|
|
|
11
|
BlackRock Fund Advisors
San Francisco,
California
|
$5.49M
|
+$4.18M
|
+158,919
|
New
|
|
|
12
|
|
$4.93M
|
+$3.75M
|
+142,754
|
New
|
|
|
13
|
Omega Fund Management
Boston,
Massachusetts
|
$3.63M
|
+$2.76M
|
+105,007
|
New
|
|
|
14
|
EcoR1 Capital
San Francisco,
California
|
$3.04M
|
+$2.31M
|
+87,921
|
New
|
|
|
15
|
|
$2.95M
|
+$2.25M
|
+85,470
|
New
|
|
|
16
|
|
$2.5M
|
+$1.91M
|
+72,500
|
New
|
|
|
17
|
|
$2.4M
|
+$1.83M
|
+69,641
|
New
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.99M
|
+$1.52M
|
+57,666
|
New
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$1.96M
|
+$1.49M
|
+56,809
|
New
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$1.19M
|
+$907K
|
+34,511
|
New
|
|
|
21
|
SG Americas Securities
New York
|
$1.16M
|
+$880K
|
+33,484
|
New
|
|
|
22
|
BlackRock Investment Management
Wilmington,
Delaware
|
$877K
|
+$667K
|
+25,381
|
New
|
|
|
23
|
Barclays
London,
United Kingdom
|
$824K
|
+$637K
|
+24,240
|
New
|
|
|
24
|
Bank of New York Mellon
New York
|
$595K
|
+$453K
|
+17,225
|
New
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$518K
|
+$394K
|
+14,999
|
New
|
|
