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Precision BioSciences

69 hedge funds and large institutions have $62.8M invested in Precision BioSciences in 2025 Q4 according to their latest regulatory filings, with 21 funds opening new positions, 22 increasing their positions, 7 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

214% more repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 7

163% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 8

145% more capital invested

Capital invested by funds: $25.7M → $62.8M (+$37.2M)

74.51% more ownership

Funds ownership: 39.45%113.95% (+75%)

23% more funds holding

Funds holding: 5669 (+13)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1K

Holders
69
Holders Change
+13
Holders Change %
+23.21%
% of All Funds
0.84%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
21
Increased
22
Reduced
7
Closed
8
Calls
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
EAM
1
Empery Asset Management
New York
$9.13M +$12.5M +2,194,635 New
Aberdeen Group
2
Aberdeen Group
United Kingdom
$8.9M +$12.1M +2,138,603 New
OCA
3
Octagon Capital Advisors
New York
$7.98M +$10.9M +1,917,995 New
BL
4
Bleichroeder LP
New York
$6.92M +$3.33M +587,500 +55%
BFM
5
Boothbay Fund Management
New York
$4.43M +$5.04M +887,515 +497%
LCM
6
Lynx1 Capital Management
Puerto Rico
$4.13M -$276K -48,683 -5%
Vanguard Group
7
Vanguard Group
Pennsylvania
$3.77M +$2.35M +414,186 +84%
Alyeska Investment Group
8
Alyeska Investment Group
Illinois
$3.32M +$4.53M +798,000 New
DCM
9
Driehaus Capital Management
Illinois
$3.28M +$4.47M +787,700 New
SFM
10
Sphera Funds Management
Israel
$1.65M +$2.25M +396,116 New
Renaissance Technologies
11
Renaissance Technologies
New York
$1.36M +$740K +130,300 +66%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$939K +$659K +116,136 +106%
BlackRock
13
BlackRock
New York
$700K +$395K +69,632 +71%
Two Sigma Investments
14
Two Sigma Investments
New York
$580K +$320K +56,439 +68%
Morgan Stanley
15
Morgan Stanley
New York
$415K +$507K +89,331 +853%
6CM
16
683 Capital Management
New York
$404K +$551K +97,085 New
Commonwealth Equity Services
17
Commonwealth Equity Services
Massachusetts
$388K +$213K +37,461 +67%
Northern Trust
18
Northern Trust
Illinois
$360K +$275K +48,397 +127%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$347K +$178K +31,419 +60%
Marshall Wace
20
Marshall Wace
United Kingdom
$295K +$403K +70,915 New
QL
21
Quarry LP
New York
$284K +$50.7K +8,936 +15%
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$277K +$378K +66,581 New
QC
23
Quadrature Capital
United Kingdom
$258K +$273K +48,158 +345%
BCM
24
Bridgeway Capital Management
Texas
$258K
UBS Group
25
UBS Group
Switzerland
$255K +$209K +36,856 +151%

DTIL Hedge Fund Activity: Q4 2025 in Review

69 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Precision BioSciences (DTIL) for Q4 2025, worth a combined $62.8M — up 145% from $25.7M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new DTIL positions and 8 closed out — a net gain of 13 holders — while 22 added to existing stakes and 7 trimmed.

The largest buyer was Aberdeen Group, opening a new position worth an estimated $12.1M. The largest seller was Tang Capital Management, exiting entirely with an estimated $3.61M sold.

  • 69 institutional investors held Precision BioSciences (DTIL) as of Q4 2025, up from 56 in Q3 2025.
  • Funds reported $62.8M of Precision BioSciences stock for Q4 2025, up 145% quarter-over-quarter.
  • 21 funds opened new Precision BioSciences positions in Q4 2025 and 8 closed out, a net change of +13 holders.
  • The largest Precision BioSciences buyer in Q4 2025 was Aberdeen Group, an estimated $12.1M added.
  • The largest Precision BioSciences seller in Q4 2025 was Tang Capital Management, an estimated $3.61M sold.

Based on aggregated 13F filings for Q4 2025.