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Precision BioSciences
DTIL

78 hedge funds and large institutions have $88.1M invested in Precision BioSciences in 2026 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 24 increasing their positions, 13 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

91% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 11

85% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 13

40% more capital invested

Capital invested by funds: $62.8M → $88.1M (+$25.3M)

13% more funds holding

Funds holding: 69 → 78 (+9)

48.64% less ownership

Funds ownership: 113.95% → 65.32% (-49%)

Holders
78
Holders Change
+9
Holders Change %
+13.04%
% of All Funds
0.96%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
21
Increased
24
Reduced
13
Closed
11
Calls
$112K
Puts
–
Net Calls
+$112K
Net Calls Change
+$113K

Top Buyers

Rank Fund Capital Flow
1
AAA
Affinity Asset Advisors
New York
+$2.76M
2
Marshall Wace
Marshall Wace
United Kingdom
+$1.59M
3
OCA
Octagon Capital Advisors
New York
+$1.47M
4
DCM
Driehaus Capital Management
Illinois
+$958K
5
ACH
ArrowMark Colorado Holdings
Colorado
+$826K

Top Sellers

Rank Fund Capital Flow
1
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$3.04M
2
SFM
Sphera Funds Management
Israel
-$1.64M
3
EAM
Empery Asset Management
New York
-$1.04M
4
Renaissance Technologies
Renaissance Technologies
New York
-$477K
5
6CM
683 Capital Management
New York
-$404K
Name Holding Trade Value Shares
Change 		Change in
Stake
JF
26
Jump Financial
Illinois
$282K +$71.4K +15,483 +43%
Acadian Asset Management
27
Acadian Asset Management
Massachusetts
$244K -$53.3K -11,547 -21%
Squarepoint
28
Squarepoint
New York
$241K +$202K +43,848 New
SSA
29
Schonfeld Strategic Advisors
New York
$223K +$187K +40,552 New
SFM
30
Sphera Funds Management
Israel
$220K -$1.64M -356,116 -90%
VCIM
31
Velan Capital Investment Management
Georgia
$220K +$92.3K +20,000 +100%
Goldman Sachs
32
Goldman Sachs
New York
$219K +$183K +39,752 New
Hudson Bay Capital Management
33
Hudson Bay Capital Management
Connecticut
$204K +$171K +37,141 New
Point72 Asset Management
34
Point72 Asset Management
Connecticut
$196K +$27.6K +5,986 +20%
BHCM
35
Brevan Howard Capital Management
Jersey
$189K +$159K +34,442 New
QC
36
Quadrature Capital
United Kingdom
$178K -$138K -29,848 -48%
Millennium Management
37
Millennium Management
New York
$152K +$128K +27,684 New
Bank of America
38
Bank of America
North Carolina
$151K +$79.2K +17,172 +168%
TI
39
Trexquant Investment
Connecticut
$143K -$65.5K -14,190 -35%
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$142K +$118K +25,667 +31,301%
Charles Schwab
41
Charles Schwab
California
$110K +$92.3K +20,000 New
Qube Research & Technologies (QRT)
42
Qube Research & Technologies (QRT)
United Kingdom
$107K +$89.7K +19,443 New
Focus Partners Wealth
43
Focus Partners Wealth
Massachusetts
$105K +$88.2K +19,111 New
Jane Street
44
Jane Street
New York
$104K +$87.6K +18,993 New
QCM
45
Quantinno Capital Management
New York
$104K +$87.5K +18,975 New
MFS
46
Miller Financial Services
Michigan
$93.5K +$9.23K +2,000 +13%
HSA
47
HBK Sorce Advisory
Pennsylvania
$78.2K +$600 +130 +1%
LPL Financial
48
LPL Financial
California
$71.7K -$4.63K -1,003 -7%
Citigroup
49
Citigroup
New York
$71.3K +$59.8K +12,972 New
VGA
50
Vanguard Global Advisers
Pennsylvania
$59.8K +$50.2K +10,881 New
1
2
3 4

DTIL Hedge Fund Activity: Q1 2026 in Review

78 of the 8,128 institutional investors tracked by Wall St. Rank reported a position in Precision BioSciences (DTIL) for Q1 2026, worth a combined $88.1M — up 40% from $62.8M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new DTIL positions and 11 closed out — a net gain of 10 holders — while 24 added to existing stakes and 13 trimmed.

The largest buyer was Affinity Asset Advisors, opening a new position worth an estimated $2.76M. The largest seller was Alyeska Investment Group, cutting an estimated $3.04M.

  • 78 institutional investors held Precision BioSciences (DTIL) as of Q1 2026, up from 69 in Q4 2025.
  • Funds reported $88.1M of Precision BioSciences stock for Q1 2026, up 40% quarter-over-quarter.
  • 21 funds opened new Precision BioSciences positions in Q1 2026 and 11 closed out, a net change of +10 holders.
  • The largest Precision BioSciences buyer in Q1 2026 was Affinity Asset Advisors, an estimated $2.76M added.
  • The largest Precision BioSciences seller in Q1 2026 was Alyeska Investment Group, an estimated $3.04M sold.

Based on aggregated 13F filings for Q1 2026.