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Precision BioSciences

69 hedge funds and large institutions have $62.8M invested in Precision BioSciences in 2025 Q4 according to their latest regulatory filings, with 21 funds opening new positions, 22 increasing their positions, 7 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

214% more repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 7

163% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 8

145% more capital invested

Capital invested by funds: $25.7M → $62.8M (+$37.2M)

74.51% more ownership

Funds ownership: 39.45%113.95% (+75%)

23% more funds holding

Funds holding: 5669 (+13)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1K

Holders
69
Holders Change
+13
Holders Change %
+23.21%
% of All Funds
0.84%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
21
Increased
22
Reduced
7
Closed
8
Calls
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
OAC
26
OMERS Administration Corp
Ontario, Canada
$253K +$345K +60,700 New
State Street
27
State Street
Massachusetts
$246K +$119K +20,900 +55%
Acadian Asset Management
28
Acadian Asset Management
Massachusetts
$233K -$358K -63,044 -53%
TI
29
Trexquant Investment
Connecticut
$167K +$229K +40,256 New
GCP
30
GSA Capital Partners
United Kingdom
$161K +$119K +21,045 +119%
XT
31
XTX Topco
Cayman Islands
$149K +$204K +35,929 New
JF
32
Jump Financial
Illinois
$149K +$203K +35,790 New
Point72 Asset Management
33
Point72 Asset Management
Connecticut
$123K +$168K +29,607 New
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$98.8K -$113K -19,884 -46%
VCIM
35
Velan Capital Investment Management
Georgia
$83.2K
Corient Private Wealth
36
Corient Private Wealth
Florida
$83.2K +$56.8K +10,000 +100%
Citadel Advisors
37
Citadel Advisors
Florida
$65.5K -$36.3K -6,394 -29%
MFS
38
Miller Financial Services
Michigan
$62.4K +$28.4K +5,000 +50%
LPL Financial
39
LPL Financial
California
$58.4K +$11.4K +2,000 +17%
OQS
40
Occudo Quantitative Strategies
Florida
$52.3K +$71.3K +12,560 New
EGM
41
Engineers Gate Manager
New York
$43.1K +$58.8K +10,354 New
Bank of America
42
Bank of America
North Carolina
$42.6K +$57K +10,038 +4,873%
HSA
43
HBK Sorce Advisory
Pennsylvania
$38.1K +$57K +10,034 New
Barclays
44
Barclays
United Kingdom
$21.7K +$27.4K +4,827 +1,257%
AF
45
Allworth Financial
California
$19.8K
VC
46
Vivo Capital
California
$19.4K
Simplex Trading
47
Simplex Trading
Illinois
$14.2K +$19.4K +3,413 New
NFSG
48
Newbridge Financial Services Group
Florida
$6.66K
Rockefeller Capital Management
49
Rockefeller Capital Management
New York
$4.16K
CW
50
CrossGen Wealth
North Carolina
$4.16K +$5.68K +1,000 New

DTIL Hedge Fund Activity: Q4 2025 in Review

69 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Precision BioSciences (DTIL) for Q4 2025, worth a combined $62.8M — up 145% from $25.7M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new DTIL positions and 8 closed out — a net gain of 13 holders — while 22 added to existing stakes and 7 trimmed.

The largest buyer was Aberdeen Group, opening a new position worth an estimated $12.1M. The largest seller was Tang Capital Management, exiting entirely with an estimated $3.61M sold.

  • 69 institutional investors held Precision BioSciences (DTIL) as of Q4 2025, up from 56 in Q3 2025.
  • Funds reported $62.8M of Precision BioSciences stock for Q4 2025, up 145% quarter-over-quarter.
  • 21 funds opened new Precision BioSciences positions in Q4 2025 and 8 closed out, a net change of +13 holders.
  • The largest Precision BioSciences buyer in Q4 2025 was Aberdeen Group, an estimated $12.1M added.
  • The largest Precision BioSciences seller in Q4 2025 was Tang Capital Management, an estimated $3.61M sold.

Based on aggregated 13F filings for Q4 2025.