|
1
|
Close Asset Management
London,
United Kingdom
|
$76K
|
–
|
–
|
–
|
|
|
2
|
|
–
|
-$153M
|
-7,582,396
|
Closed
|
|
|
3
|
|
–
|
-$116M
|
-5,763,585
|
Closed
|
|
|
4
|
State Street
Boston,
Massachusetts
|
–
|
-$78.3M
|
-3,886,181
|
Closed
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$74.7M
|
-3,707,210
|
Closed
|
|
|
6
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
–
|
-$62.1M
|
-3,080,237
|
Closed
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
–
|
-$54.1M
|
-2,682,596
|
Closed
|
|
|
8
|
Aquilo Capital Management
San Francisco,
California
|
–
|
-$49.5M
|
-2,456,595
|
Closed
|
|
|
9
|
|
–
|
-$35M
|
-1,736,277
|
Closed
|
|
|
10
|
|
–
|
-$31.1M
|
-1,542,476
|
Closed
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
–
|
-$27.3M
|
-1,352,048
|
Closed
|
|
|
12
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
–
|
-$27.2M
|
-1,350,558
|
Closed
|
|
|
13
|
Maverick Capital
Dallas,
Texas
|
–
|
-$26.4M
|
-1,310,530
|
Closed
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
–
|
-$26.2M
|
-1,299,372
|
Closed
|
|
|
15
|
Commodore Capital
New York
|
–
|
-$26.1M
|
-1,292,251
|
Closed
|
|
|
16
|
EcoR1 Capital
San Francisco,
California
|
–
|
-$25.2M
|
-1,249,812
|
Closed
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$24M
|
-1,190,676
|
Closed
|
|
|
18
|
UBS Group
Zurich,
Switzerland
|
–
|
-$22.2M
|
-1,101,275
|
Closed
|
|
|
19
|
Palo Alto Investors
Palo Alto,
California
|
–
|
-$17.3M
|
-855,713
|
Closed
|
|
|
20
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
–
|
-$16.3M
|
-806,987
|
Closed
|
|
|
21
|
Great Point Partners
Greenwich,
Connecticut
|
–
|
-$16.1M
|
-799,999
|
Closed
|
|
|
22
|
|
–
|
-$16.1M
|
-798,544
|
Closed
|
|
|
23
|
Two Sigma Advisers
New York
|
–
|
-$15.4M
|
-765,550
|
Closed
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
–
|
-$15.4M
|
-764,310
|
Closed
|
|
|
25
|
Eagle Asset Management
St Petersburg,
Florida
|
–
|
-$14.3M
|
-709,674
|
Closed
|
|
