|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$235M
|
+$36.5M
|
+1,426,450
|
+31%
|
|
|
2
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$130M
|
+$15.3M
|
+600,000
|
+22%
|
|
|
3
|
Avidity Partners Management
Dallas,
Texas
|
$126M
|
+$37.3M
|
+1,461,282
|
+84%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$113M
|
–
|
–
|
–
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$101M
|
+$64M
|
+2,503,311
|
+3,367%
|
|
|
6
|
Octagon Capital Advisors
New York
|
$95.1M
|
+$1.92M
|
+75,000
|
+3%
|
|
|
7
|
Point72 Asset Management
Stamford,
Connecticut
|
$80.4M
|
+$16.6M
|
+649,443
|
+47%
|
|
|
8
|
TCG Crossover Management
Palo Alto,
California
|
$66M
|
+$4.47M
|
+175,000
|
+12%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$64.6M
|
+$5.01M
|
+196,117
|
+14%
|
|
|
10
|
|
$52.7M
|
-$478K
|
-18,690
|
-1%
|
|
|
11
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$51.8M
|
-$29.8M
|
-1,166,358
|
-47%
|
|
|
12
|
Vestal Point Capital
New York
|
$46.4M
|
-$51.6M
|
-2,020,000
|
-63%
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$39.9M
|
+$8.91M
|
+348,457
|
+52%
|
|
|
14
|
|
$37.8M
|
-$1M
|
-39,197
|
-4%
|
|
|
15
|
AllianceBernstein
Nashville,
Tennessee
|
$33.5M
|
-$8.24M
|
-322,438
|
-27%
|
|
|
16
|
Braidwell
Stamford,
Connecticut
|
$32.9M
|
+$21.3M
|
+835,057
|
New
|
|
|
17
|
Baker Bros. Advisors
New York
|
$31.1M
|
–
|
–
|
–
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$29.4M
|
+$19.1M
|
+748,003
|
New
|
|
|
19
|
Silverarc Capital Management
Boston,
Massachusetts
|
$26.6M
|
+$14.8M
|
+579,160
|
+605%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$26.4M
|
-$3.81M
|
-149,089
|
-18%
|
|
|
21
|
Catalio Capital Management
New York
|
$26.3M
|
-$2.02M
|
-78,912
|
-11%
|
|
|
22
|
Sio Capital Management
New York
|
$22.7M
|
+$8.73M
|
+341,680
|
+145%
|
|
|
23
|
Marshall Wace
London,
United Kingdom
|
$22.5M
|
+$14.6M
|
+572,938
|
New
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$21.1M
|
+$1.32M
|
+51,515
|
+11%
|
|
|
25
|
Franklin Resources
San Mateo,
California
|
$17.7M
|
+$11.5M
|
+450,311
|
New
|
|
