|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$54.8M
|
–
|
–
|
–
|
|
|
2
|
|
$42.3M
|
–
|
–
|
–
|
|
|
3
|
New Leaf Venture Partners
New York
|
$16.1M
|
–
|
–
|
–
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$12.1M
|
+$3.62M
|
+460,103
|
+42%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$9.8M
|
+$137K
|
+17,400
|
+1%
|
|
|
6
|
Janus Henderson Investors US
Denver,
Colorado
|
$9.2M
|
-$300K
|
-38,086
|
-3%
|
|
|
7
|
Jennison Associates
New York
|
$5.83M
|
+$26.4K
|
+3,347
|
+0.5%
|
|
|
8
|
PFM Health Sciences
San Francisco,
California
|
$5.52M
|
-$710K
|
-90,190
|
-11%
|
|
|
9
|
|
$2.15M
|
+$788K
|
+100,000
|
+57%
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$2.13M
|
–
|
–
|
–
|
|
|
11
|
|
$1.87M
|
+$632K
|
+80,200
|
+51%
|
|
|
12
|
Weiss Multi-Strategy Advisers
New York
|
$1.57M
|
+$308K
|
+39,110
|
+24%
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$1.13M
|
-$60K
|
-7,617
|
-5%
|
|
|
14
|
Asset Management One
Tokyo,
Japan
|
$1.05M
|
-$2.17K
|
-275
|
-0.2%
|
|
|
15
|
Foresite Capital Management III
Larkspur,
California
|
$770K
|
–
|
–
|
–
|
|
|
16
|
Vanguard Group
Malvern,
Pennsylvania
|
$610K
|
+$405K
|
+51,388
|
+194%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$513K
|
+$163K
|
+20,700
|
+46%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$462K
|
+$465K
|
+59,064
|
New
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$438K
|
+$11.7K
|
+1,486
|
+3%
|
|
|
20
|
BlackRock Institutional Trust
San Francisco,
California
|
$228K
|
+$701
|
+89
|
+0.3%
|
|
|
21
|
BlackRock Investment Management
Wilmington,
Delaware
|
$131K
|
+$63.3K
|
+8,039
|
+92%
|
|
|
22
|
Partner Investment Management
San Francisco,
California
|
$125K
|
-$18.3K
|
-2,326
|
-12%
|
|
|
23
|
|
$124K
|
-$31.2K
|
-3,958
|
-20%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$103K
|
–
|
–
|
–
|
|
|
25
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$94K
|
+$12.8K
|
+1,624
|
+16%
|
|
