|
1
|
Wellington Management Group
Boston,
Massachusetts
|
–
|
-$75.7M
|
-4,995,870
|
Closed
|
|
|
2
|
|
–
|
-$63.4M
|
-4,182,738
|
Closed
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
–
|
-$53.2M
|
-3,506,649
|
Closed
|
|
|
4
|
Fred Alger Management
New York
|
–
|
-$46.3M
|
-3,054,440
|
Closed
|
|
|
5
|
Polar Capital
London,
United Kingdom
|
–
|
-$43.1M
|
-2,841,540
|
Closed
|
|
|
6
|
Great Point Partners
Greenwich,
Connecticut
|
–
|
-$39.7M
|
-2,621,333
|
Closed
|
|
|
7
|
Oracle Investment Management
Greenwich,
Connecticut
|
–
|
-$38.3M
|
-2,528,311
|
Closed
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$36.7M
|
-2,422,611
|
Closed
|
|
|
9
|
PFM Health Sciences
San Francisco,
California
|
–
|
-$34.4M
|
-2,271,180
|
Closed
|
|
|
10
|
Bank of America
Charlotte,
North Carolina
|
–
|
-$30.6M
|
-2,019,249
|
Closed
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$29.7M
|
-1,960,328
|
Closed
|
|
|
12
|
Franklin Resources
San Mateo,
California
|
–
|
-$22.7M
|
-1,497,680
|
Closed
|
|
|
13
|
State Street
Boston,
Massachusetts
|
–
|
-$14.9M
|
-979,896
|
Closed
|
|
|
14
|
Millennium Management
New York
|
–
|
-$14.3M
|
-945,455
|
Closed
|
|
|
15
|
EARNEST Partners
Atlanta,
Georgia
|
–
|
-$12.2M
|
-807,191
|
Closed
|
|
|
16
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
–
|
-$12.1M
|
-800,000
|
Closed
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
–
|
-$9.85M
|
-650,000
|
Closed
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$9.82M
|
-647,703
|
Closed
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
–
|
-$8.75M
|
-577,059
|
Closed
|
|
|
20
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
–
|
-$8.64M
|
-570,000
|
Closed
|
|
|
21
|
Paradigm Capital Management Inc
Albany,
New York
|
–
|
-$8.6M
|
-567,300
|
Closed
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
–
|
-$8.33M
|
-549,202
|
Closed
|
|
|
23
|
Sofinnova Investments
Menlo Park,
California
|
–
|
-$8.27M
|
-545,466
|
Closed
|
|
|
24
|
|
–
|
-$7.84M
|
-517,494
|
Closed
|
|
|
25
|
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
–
|
-$7.5M
|
-494,858
|
Closed
|
|
