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DAWN

Day One Biopharmaceuticals

Delisted

DAWN was delisted on the 22nd of April, 2026.

183 hedge funds and large institutions have $758M invested in Day One Biopharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 44 funds opening new positions, 74 increasing their positions, 43 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

72% more repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 43

33% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 33

26% more capital invested

Capital invested by funds: $603M → $758M (+$155M)

10% more call options, than puts

Call options by funds: $7.37M | Put options by funds: $6.69M

6% more funds holding

Funds holding: 172183 (+11)

4.28% less ownership

Funds ownership: 83.57%79.29% (-4.3%)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
183
Holders Change
+11
Holders Change %
+6.4%
% of All Funds
2.22%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
44
Increased
74
Reduced
43
Closed
33
Calls
$7.37M
Puts
$6.69M
Net Calls
+$682K
Net Calls Change
+$473K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$82.4M -$1.37M -163,881 -2%
AVLSA
2
Atlas Venture Life Science Advisors
Massachusetts
$59.8M -$148K -17,697 -0.3%
Vanguard Group
3
Vanguard Group
Pennsylvania
$58.6M +$844K +101,047 +2%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$53.3M -$36.6M -4,380,660 -43%
VPC
5
Vestal Point Capital
New York
$48.5M +$21.1M +2,525,000 +94%
State Street
6
State Street
Massachusetts
$40M +$8.76M +1,049,122 +32%
DM
7
Deerfield Management
New York
$34.7M -$8.21M -982,282 -21%
Pictet Asset Management
8
Pictet Asset Management
Switzerland
$27.9M +$5.16M +617,668 +26%
ACM
9
AIGH Capital Management
Maryland
$18.6M +$3.94M +471,529 +31%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$17.5M +$974K +116,574 +7%
Hudson Bay Capital Management
11
Hudson Bay Capital Management
Connecticut
$15.8M +$3.17M +380,000 +29%
Morgan Stanley
12
Morgan Stanley
New York
$14.4M +$2.06M +246,245 +19%
Goldman Sachs
13
Goldman Sachs
New York
$14M +$1.13M +134,797 +10%
Balyasny Asset Management
14
Balyasny Asset Management
Illinois
$13.9M +$885K +105,877 +8%
Qube Research & Technologies (QRT)
15
Qube Research & Technologies (QRT)
United Kingdom
$13.9M +$2.66M +318,893 +27%
Citadel Advisors
16
Citadel Advisors
Florida
$12.7M +$5.82M +696,400 +105%
Millennium Management
17
Millennium Management
New York
$12.6M +$5.49M +656,599 +95%
Renaissance Technologies
18
Renaissance Technologies
New York
$12.2M +$3.34M +399,608 +44%
JFG
19
Jefferies Financial Group
New York
$10.5M +$9.37M +1,121,502 New
Bank of America
20
Bank of America
North Carolina
$10.1M -$903K -108,033 -9%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$9.67M -$1.55M -185,972 -15%
DCM
22
DAFNA Capital Management
California
$9.31M
Jane Street
23
Jane Street
New York
$7.88M +$4.73M +565,810 +203%
MCO
24
MAK Capital One
New York
$7.7M -$5.2M -622,256 -43%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$6.87M +$5.92M +708,806 +2,457%

DAWN Hedge Fund Activity: Q4 2025 in Review

183 of the 8,225 institutional investors tracked by Wall St. Rank reported a position in Day One Biopharmaceuticals (DAWN) for Q4 2025, worth a combined $758M — up 26% from $603M a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new DAWN positions and 33 closed out — a net gain of 11 holders — while 74 added to existing stakes and 43 trimmed.

The largest buyer was Vestal Point Capital, adding an estimated $21.1M. The largest seller was Fidelity Investments, cutting an estimated $36.6M.

  • 183 institutional investors held Day One Biopharmaceuticals (DAWN) as of Q4 2025, up from 172 in Q3 2025.
  • Funds reported $758M of Day One Biopharmaceuticals stock for Q4 2025, up 26% quarter-over-quarter.
  • 44 funds opened new Day One Biopharmaceuticals positions in Q4 2025 and 33 closed out, a net change of +11 holders.
  • The largest Day One Biopharmaceuticals buyer in Q4 2025 was Vestal Point Capital, an estimated $21.1M added.
  • The largest Day One Biopharmaceuticals seller in Q4 2025 was Fidelity Investments, an estimated $36.6M sold.

Based on aggregated 13F filings for Q4 2025.