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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$582M +$266M +7,647,189 +77%
BlackRock
2
BlackRock
New York
$518M +$3.97M +114,089 +0.7%
Vanguard Group
3
Vanguard Group
Pennsylvania
$396M +$4.67M +134,291 +1%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$372M +$33.1M +951,380 +9%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$259M -$5.6M -161,061 -2%
State Street
6
State Street
Massachusetts
$211M +$10M +287,752 +5%
DTC
7
Deep Track Capital
Connecticut
$121M +$20M +576,147 +19%
UBS Group
8
UBS Group
Switzerland
$101M +$32.6M +936,446 +44%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$98.9M +$1.98M +56,961 +2%
VPC
10
Vestal Point Capital
New York
$98.3M +$13.4M +384,469 +15%
PCH
11
Polar Capital Holdings
United Kingdom
$92.5M +$11.9M +342,664 +14%
RI
12
RTW Investments
New York
$89.9M
Bank of America
13
Bank of America
North Carolina
$87.4M -$1.99M -57,306 -2%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$61.7M -$4.45M -127,919 -6%
Pictet Asset Management
15
Pictet Asset Management
Switzerland
$51.1M -$14.3M -409,936 -21%
AllianceBernstein
16
AllianceBernstein
Tennessee
$45.8M -$4.78M -137,487 -9%
Northern Trust
17
Northern Trust
Illinois
$45.6M -$2.37M -68,125 -5%
Charles Schwab
18
Charles Schwab
California
$44.8M +$1.54M +44,260 +3%
MAM
19
Melqart Asset Management
United Kingdom
$43.8M +$11.4M +327,272 +33%
JP Morgan Chase
20
JP Morgan Chase
New York
$43.5M -$278K -7,994 -0.6%
AC
21
Armistice Capital
New York
$43.4M +$10.1M +288,959 +28%
Citadel Advisors
22
Citadel Advisors
Florida
$42.9M +$5.15M +148,095 +13%
Goldman Sachs
23
Goldman Sachs
New York
$42.1M -$3.09M -88,975 -7%
Principal Financial Group
24
Principal Financial Group
Iowa
$39.1M +$19.3M +554,894 +88%
Norges Bank
25
Norges Bank
Norway
$39.1M +$249K +7,153 +0.6%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.