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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Squarepoint
176
Squarepoint
New York
$608K -$2.97M -85,480 -82%
TC
177
Tejara Capital
United Kingdom
$605K +$637K +18,300 New
Stifel Financial
178
Stifel Financial
Missouri
$586K -$33.7K -968 -5%
X
179
Xponance
Pennsylvania
$552K +$5.18K +149 +0.9%
DIA
180
Dana Investment Advisors
Wisconsin
$549K -$13.9K -401 -2%
ORI
181
Oak Ridge Investments
Illinois
$537K -$29.4K -845 -5%
NSEDCP
182
NJ State Employees Deferred Compensation Plan
New Jersey
$512K
EP
183
Edgestream Partners
New Jersey
$505K -$102K -2,941 -16%
Bank of Montreal
184
Bank of Montreal
Ontario, Canada
$480K -$44K -1,266 -8%
CWM
185
CIBC World Markets
New York
$476K -$381K -10,967 -43%
VPIM
186
Vanguard Personalized Indexing Management
California
$449K +$52.5K +1,509 +12%
SOADOR
187
State of Alaska Department of Revenue
Alaska
$444K -$12.7K -365 -3%
TI
188
Tidal Investments
Wisconsin
$441K +$174K +4,995 +60%
FIA
189
FNY Investment Advisers
New York
$426K +$71K +2,040 +19%
NRD
190
Nebula Research & Development
New York
$410K +$8.56K +246 +2%
II
191
Inspire Investing
Idaho
$393K +$116K +3,337 +39%
SAM
192
Sectoral Asset Management
Quebec, Canada
$387K -$221K -6,345 -35%
GAM
193
Groupama Asset Management
France
$380K
DnB Asset Management
194
DnB Asset Management
Norway
$378K +$35.5K +1,021 +10%
TRCT
195
Tower Research Capital (TRC)
New York
$366K +$88.7K +2,551 +30%
TI
196
Trexquant Investment
Connecticut
$360K +$379K +10,894 New
HM
197
Harvest Management
New York
$355K -$34.8K -1,000 -9%
Public Employees Retirement Association of Colorado
198
Public Employees Retirement Association of Colorado
Colorado
$349K
HighTower Advisors
199
HighTower Advisors
Illinois
$344K -$32.3K -929 -8%
CG
200
Cynosure Group
Utah
$343K +$89.9K +2,584 +33%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.