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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
State Board of Administration of Florida Retirement System
151
State Board of Administration of Florida Retirement System
Florida
$941K
WG
152
Winton Group
United Kingdom
$930K +$136K +3,904 +16%
Thrivent Financial for Lutherans
153
Thrivent Financial for Lutherans
Minnesota
$929K +$15.6K +449 +2%
NMIMC
154
Northwestern Mutual Investment Management Company
Wisconsin
$881K +$14.9K +427 +2%
PFSRSONJ
155
Police & Firemen's Retirement System of New Jersey
New Jersey
$867K +$45.9K +1,320 +5%
Prudential Financial
156
Prudential Financial
New Jersey
$866K -$313K -9,005 -26%
Wolverine Trading
157
Wolverine Trading
Illinois
$856K +$443K +12,742 +98%
Universal-Beteiligungs- und Servicegesellschaft
158
Universal-Beteiligungs- und Servicegesellschaft
Germany
$832K +$8.21K +236 +0.9%
Pathstone Holdings
159
Pathstone Holdings
New Jersey
$815K -$189K -5,441 -18%
OPERF
160
Oregon Public Employees Retirement Fund
Oregon
$807K +$13.9K +400 +2%
Federated Hermes
161
Federated Hermes
Pennsylvania
$806K -$336K -9,656 -28%
KK
162
KLP Kapitalforvaltning
Norway
$793K +$13.9K +400 +2%
NIM
163
NEOS Investment Management
Connecticut
$793K -$299K -8,592 -26%
TE
164
Tema ETFs
New York
$793K -$299K -8,592 -26%
CUAMC
165
China Universal Asset Management Company
China
$793K +$8.21K +236 +1%
NMERB
166
New Mexico Educational Retirement Board
New Mexico
$776K
Nomura Holdings
167
Nomura Holdings
Japan
$770K -$182K -5,222 -18%
HCM
168
Harvey Capital Management
Florida
$738K -$22.6K -650 -3%
Marshall Wace
169
Marshall Wace
United Kingdom
$701K -$69.8M -2,007,567 -99%
CC
170
Carlson Capital
Texas
$677K +$452K +13,000 +173%
LPL Financial
171
LPL Financial
California
$653K +$171K +4,917 +33%
D.E. Shaw & Co
172
D.E. Shaw & Co
New York
$631K +$201K +5,782 +43%
CM
173
Caption Management
Oklahoma
$628K -$1.38M -39,739 -68%
EFM
174
E Fund Management
China
$625K +$179K +5,136 +37%
Natixis Advisors
175
Natixis Advisors
Massachusetts
$610K -$939K -26,992 -59%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.