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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
VOYA Investment Management
126
VOYA Investment Management
Georgia
$1.35M -$525K -15,084 -27%
Skandinaviska Enskilda Banken (SEB)
127
Skandinaviska Enskilda Banken (SEB)
Sweden
$1.3M -$3.88M -111,519 -74%
New York State Common Retirement Fund
128
New York State Common Retirement Fund
New York
$1.27M +$104K +3,000 +8%
PA
129
Profund Advisors
Maryland
$1.27M +$153K +4,413 +13%
Victory Capital Management
130
Victory Capital Management
Texas
$1.26M +$575K +16,538 +77%
GC
131
Guggenheim Capital
Illinois
$1.25M +$42.1K +1,209 +3%
Comerica Bank
132
Comerica Bank
Texas
$1.2M -$7.19M -206,849 -85%
ZDA
133
Zweig-DiMenna Associates
New York
$1.18M +$1.24M +35,600 New
PCM
134
Prelude Capital Management
New York
$1.17M +$242K +6,947 +24%
AIP
135
Ameritas Investment Partners
Nebraska
$1.16M +$8.87K +255 +0.7%
MCM
136
Moore Capital Management
New York
$1.16M
LIP
137
Lighthouse Investment Partners
Florida
$1.16M +$1.22M +35,000 New
ProShare Advisors
138
ProShare Advisors
Maryland
$1.11M -$48.9K -1,405 -4%
JGC
139
J. Goldman & Co
New York
$1.11M +$1.17M +33,636 New
LSERS
140
Louisiana State Employees Retirement System
Louisiana
$1.11M +$17.4K +500 +2%
ASRS
141
Arizona State Retirement System
Arizona
$1.09M +$30.5K +877 +3%
GLA
142
Great Lakes Advisors
Illinois
$1.08M -$38.2K -1,097 -3%
Handelsbanken Fonder
143
Handelsbanken Fonder
Sweden
$1.07M
Zurich Cantonal Bank
144
Zurich Cantonal Bank
Switzerland
$1.07M +$104K +2,994 +10%
Dimensional Fund Advisors
145
Dimensional Fund Advisors
Texas
$1.06M +$36.6K +1,052 +3%
COPPSERS
146
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$1.01M +$86.1K +2,474 +9%
Teacher Retirement System of Texas
147
Teacher Retirement System of Texas
Texas
$1.01M +$11.9K +341 +1%
Envestnet Asset Management
148
Envestnet Asset Management
Illinois
$974K +$179K +5,146 +21%
OTPPB
149
Ontario Teachers' Pension Plan Board
Ontario, Canada
$963K +$494K +14,192 +95%
SOMRS
150
State of Michigan Retirement System
Michigan
$948K +$17.4K +500 +2%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.